D6RII6 · D6RII6_MOUSE
- ProteinDiscoidin domain receptor family, member 1
- GeneDdr1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids143 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score1/5
Publications for D6RII6
Collagenolysis-dependent DDR1 signalling dictates pancreatic cancer outcome.
- CategoryFunction
- SourceMGI: 99216
Tumour DDR1 promotes collagen fibre alignment to instigate immune exclusion.
- CategoryFunction
- SourceMGI: 99216
Discoidin Domain Receptor 1 Regulates Runx2 during Osteogenesis of Osteoblasts and Promotes Bone Ossification via Phosphorylation of p38.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 99216
Discoidin Domain Receptor 1 is a therapeutic target for neurodegenerative diseases.
- CategoryFunction
- SourceMGI: 99216
Discoidin Domain Receptor 1 (DDR1) Is Necessary for Tissue Homeostasis in Pancreatic Injury and Pathogenesis of Pancreatic Ductal Adenocarcinoma.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 99216
Discoidin domain receptor 1 regulates endochondral ossification through terminal differentiation of chondrocytes.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 99216
Loss of Discoidin Domain Receptor 1 Predisposes Mice to Periodontal Breakdown.
- CategoriesFunction, Expression, Phenotypes & Variants
- SourceMGI: 99216
DDR1 promotes breast tumor growth by suppressing antitumor immunity.
- CategoriesFunction, Expression
- SourceMGI: 99216
Discoidin Domain Receptor 1 (DDR1) tyrosine kinase is upregulated in PKD kidneys but does not play a role in the pathogenesis of polycystic kidney disease.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 99216
Diabetic Vascular Calcification Mediated by the Collagen Receptor Discoidin Domain Receptor 1 via the Phosphoinositide 3-Kinase/Akt/Runt- Related Transcription Factor 2 Signaling Axis.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 99216
Tumor-extrinsic discoidin domain receptor 1 promotes mammary tumor growth by regulating adipose stromal interleukin 6 production in mice.
- CategoriesFunction, Interaction
- SourceMGI: 99216
Discoidin Domain Receptor 1 Mediates Myosin-Dependent Collagen Contraction.
- CategoriesFunction, Interaction
- SourceMGI: 99216
Discoidin domain receptor 1 kinase activity is required for regulating collagen IV synthesis.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 99216
Collagen Fibril Ultrastructure in Mice Lacking Discoidin Domain Receptor 1.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 99216
Minor Type IV Collagen alpha5 Chain Promotes Cancer Progression through Discoidin Domain Receptor-1.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 99216