D6RHK4 · D6RHK4_MOUSE
- ProteinTumor necrosis factor receptor superfamily, member 8
- GeneTnfrsf8
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids322 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Publications for D6RHK4
Expression of the costimulatory receptor CD30 is regulated by both CD28 and cytokines.
- CategoriesFunction
- SourceMGI: 99908
- PubMed
- Europe PMC
- J Immunol 160:2180-2187 ()
Mapped toImpaired negative selection of T cells in Hodgkin's disease antigen CD30- deficient mice.
- CategoriesFunction
- SourceMGI: 99908
Mapped toStructure and expression of murine CD30 and its role in cytokine production.
- CategoriesSequences
- SourceMGI: 99908
- PubMed
- Europe PMC
- J. Immunol. 156:442-449 ()
Assignment of the mouse homologues of 6 loci from HSA1p to chromosomes 3 and 4.
- CategoriesSequences
- SourceMGI: 99908
The short-chain fatty acid acetate coordinates with CD30 to modulate T- cell survival.
- CategoriesFunction
- SourceMGI: 99908
cis interaction of CD153 with TCR/CD3 is crucial for the pathogenic activation of senescence-associated T cells.
- CategoriesFunction, Interaction
- SourceMGI: 99908
Combination blockade of OX40L and CD30L inhibits allergen-driven memory T<sub>H</sub>2 cell reactivity and lung inflammation.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 99908
Essential Role for CD30-Transglutaminase 2 Axis in Memory Th1 and Th17 Cell Generation.
- CategoriesFunction
- SourceMGI: 99908
CD30 ligand/CD30 interaction is involved in pathogenesis of inflammatory bowel disease.
- CategoriesFunction, Interaction
- SourceMGI: 99908
Abrogation of CD30 and OX40 signals prevents autoimmune disease in FoxP3- deficient mice.
- CategoriesFunction
- SourceMGI: 99908
The central role of CD30L/CD30 interactions in allergic rhinitis pathogenesis in mice.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 99908
The survival of memory CD4+ T cells within the gut lamina propria requires OX40 and CD30 signals.
- CategoriesFunction
- SourceMGI: 99908
NK cells protect secondary lymphoid tissue from cytomegalovirus via a CD30-dependent mechanism.
- CategoriesFunction
- SourceMGI: 99908