D6RGQ8 · D6RGQ8_MOUSE
- ProteinRho guanine nucleotide exchange factor 11
- GeneArhgef11
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids608 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | G protein-coupled receptor binding | |
Molecular Function | guanyl-nucleotide exchange factor activity | |
Biological Process | G protein-coupled receptor signaling pathway | |
Biological Process | positive regulation of L-glutamate import across plasma membrane |
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionD6RGQ8
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-40 | Disordered | ||||
Sequence: MSIRLPHSIDRLSSLSSLGDSTPERTSPSHHRQPSDTSET | ||||||
Compositional bias | 7-24 | Polar residues | ||||
Sequence: HSIDRLSSLSSLGDSTPE | ||||||
Domain | 47-111 | PDZ | ||||
Sequence: CVIIQKDQHGFGFTVSGDRIVLVQSVRPGGAAMRAGVKEGDRIIKVNGTMVTNSSHLEVVKLIKS | ||||||
Region | 128-165 | Disordered | ||||
Sequence: GVSGLQQNPSLSGGPRVNPMIPPPPPPPPLPPPQHITG | ||||||
Compositional bias | 143-165 | Pro residues | ||||
Sequence: RVNPMIPPPPPPPPLPPPQHITG | ||||||
Region | 250-270 | Disordered | ||||
Sequence: GRLSVDSQEADSGLDSGTERF | ||||||
Region | 309-329 | Disordered | ||||
Sequence: QGSDAAVHPLNHQGIDQSPKP | ||||||
Domain | 353-443 | RGS | ||||
Sequence: DLEKLKSHPAYLVVFLRYIFSQADPGPLLFYLCSEVYQQTNPKDSRNLGKDIWNIFLEKNAPLRVKIPEMLQAEIDLRLRNSEDPRSALYE | ||||||
Region | 526-590 | Disordered | ||||
Sequence: RLRESRPSSTAEKTQSAPDKDKWLPFFPKTKKSSNSKKEKDALEDKKRNPILRYIGKPKSSSQSI | ||||||
Compositional bias | 540-577 | Basic and acidic residues | ||||
Sequence: QSAPDKDKWLPFFPKTKKSSNSKKEKDALEDKKRNPIL |
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length608
- Mass (Da)67,456
- Last updated2010-07-13 v1
- Checksum92F7FB8DE059610E
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q68FM7 | Q68FM7_MOUSE | Arhgef11 | 1552 | ||
E9Q0A3 | E9Q0A3_MOUSE | Arhgef11 | 1475 | ||
A0A1D5RLI4 | A0A1D5RLI4_MOUSE | Arhgef11 | 205 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 7-24 | Polar residues | ||||
Sequence: HSIDRLSSLSSLGDSTPE | ||||||
Compositional bias | 143-165 | Pro residues | ||||
Sequence: RVNPMIPPPPPPPPLPPPQHITG | ||||||
Compositional bias | 540-577 | Basic and acidic residues | ||||
Sequence: QSAPDKDKWLPFFPKTKKSSNSKKEKDALEDKKRNPIL |
Keywords
- Technical term