D6QW66 · D6QW66_PAEAL

Function

function

Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.

Catalytic activity

Pathway

Carbohydrate biosynthesis; dTDP-L-rhamnose biosynthesis.

Features

Showing features for active site, site.

118320406080100120140160180
Type
IDPosition(s)Description
Active site62Proton acceptor
Active site132Proton donor
Site138Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctiondTDP-4-dehydrorhamnose 3,5-epimerase activity
Biological ProcessdTDP-rhamnose biosynthetic process
Biological Processpolysaccharide biosynthetic process

Keywords

  • Molecular function

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    dTDP-4-dehydrorhamnose 3,5-epimerase
  • EC number
  • Alternative names
    • Thymidine diphospho-4-keto-rhamnose 3,5-epimerase

Gene names

    • Name
      rmlC

Organism names

Accessions

  • Primary accession
    D6QW66

Subcellular Location

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    183
  • Mass (Da)
    20,882
  • Last updated
    2010-07-13 v1
  • MD5 Checksum
    F2346E6A113569149DA11A50D55F8678
MNVKALPLKDAYIIEPVIHGDHRGFFMESYSKKKLNELGIYFNFIQDNQSLSLETGVIRGLHFQLNPKAQTKLIRVISGAIYDVIVDIRKSSSTFGQWVGVILSEHNHRQLLVPKGFAHGFCTLTPNTQVLYKVDEYYSPDHDRGIRWDDPSLGIDWPTSKPILSDKDRLLPVLKEAEINGFE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
HM011508
EMBL· GenBank· DDBJ
ADG29295.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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