D6NIW4 · D6NIW4_UNCAX

  • Protein
    coenzyme-B sulfoethylthiotransferase
  • Gene
    mcrA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

Catalytic activity

Cofactor

coenzyme F430 (UniProtKB | Rhea| CHEBI:60540 )

Pathway

One-carbon metabolism; methyl-coenzyme M reduction; methane from methyl-coenzyme M: step 1/1.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular Functioncoenzyme-B sulfoethylthiotransferase activity
Molecular Functionmetal ion binding
Biological Processmethanogenesis

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    coenzyme-B sulfoethylthiotransferase
  • EC number

Gene names

    • Name
      mcrA

Organism names

Accessions

  • Primary accession
    D6NIW4

PTM/Processing

Keywords

Interaction

Subunit

MCR is a hexamer of two alpha, two beta, and two gamma chains, forming a dimer of heterotrimers.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-34Methyl-coenzyme M reductase alpha subunit N-terminal
Domain82-208Methyl-coenzyme M reductase alpha subunit C-terminal

Sequence similarities

Belongs to the methyl-coenzyme M reductase alpha subunit family.

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    240
  • Mass (Da)
    25,785
  • Last updated
    2010-07-13 v1
  • Checksum
    D04496EBB72010F3
FISAYKLCAGEAAVSDFVYAAKHASAIYMGSIMPARRARGENEPGGIPFGYMADISQSFRVYPDDPVRAALEAVALGAVIYDQLYLGAYMSGGIGFTQYGSATYTDNILEDYTTWGANLVKEKFGGFSKIEPSMDVIESITNEVNKYALSQYELYPANVETHFGGSQRAAVAAAACGISVALATGNSDAGLNAFYLSQLQHKERAGRLGFYGYDLQDQCGAANVYSYRGDEGLPLELRGP

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue240

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
GU447221
EMBL· GenBank· DDBJ
ADG63252.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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