D6C5C0 · D6C5C0_9POAL

  • Protein
    S-adenosylmethionine decarboxylase proenzyme
  • Gene
    SAMDC
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    3/5

Function

Catalytic activity

Cofactor

pyruvate (UniProtKB | Rhea| CHEBI:15361 )

Note: Binds 1 pyruvoyl group covalently per subunit.

Pathway

Amine and polyamine biosynthesis; S-adenosylmethioninamine biosynthesis; S-adenosylmethioninamine from S-adenosyl-L-methionine: step 1/1.

Features

Showing features for binding site, site, active site.

TypeIDPosition(s)Description
Binding site17substrate
Binding site77substrate
Site77-78Cleavage (non-hydrolytic); by autolysis
Active site78Schiff-base intermediate with substrate; via pyruvic acid
Active site92Proton donor; for catalytic activity
Binding site237substrate
Active site243Proton acceptor; for processing activity
Active site256Proton acceptor; for processing activity
Binding site260substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionadenosylmethionine decarboxylase activity
Biological Processspermidine biosynthetic process
Biological Processspermine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    S-adenosylmethionine decarboxylase proenzyme
  • EC number

Gene names

    • Name
      SAMDC

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > PACMAD clade > Chloridoideae > Cynodonteae > Orininae > Cleistogenes

Accessions

  • Primary accession
    D6C5C0

Subcellular Location

PTM/Processing

Features

Showing features for chain, modified residue.

TypeIDPosition(s)Description
ChainPRO_50423251331-77S-adenosylmethionine decarboxylase beta chain
Modified residue78Pyruvic acid (Ser); by autocatalysis
ChainPRO_504232513478-397S-adenosylmethionine decarboxylase alpha chain

Keywords

Family & Domains

Sequence similarities

Belongs to the eukaryotic AdoMetDC family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    397
  • Mass (Da)
    43,457
  • Last updated
    2010-07-13 v1
  • Checksum
    B5D6847D458C113D
MAVMRAGDVPPVSAIGFEGYEKRLEISFSEAPIFADPNGRGLRALSRAQIDSVLDLARCTIVSELSNEAFDSYVLSESSLFVYPYRVVIKTCGTTKLLLAIPRILELAEELSLPLAAVKYSRGTFIFPDAQPSPHKNFADEVAFLNRYFGGLKSGGNAYVIGDPAKPGQKWHIYYATEYPEKPVVTLEMCMTGLDKKKASVFFKTSANGHISCAKEMTKLSGISDIIPEMEICDFDFEPCGYSMNAIHGPAFSTIHVTPEDGFSYASYEVMGFNPASLAYGDLVKRVLKCFSPSEFSVAVTIFGERDNAKTWGKKLDVESYACGNMVEEELPSGGLLVYQSFTATGEVAVGSPRSVIHSFSDDDVENESMNASSDALLCWEADAVKTEGREAKKMKY

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FJ972823
EMBL· GenBank· DDBJ
ADC45379.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

Disclaimer

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