D5X0W1 · D5X0W1_THIK1
- ProteinThreonine--tRNA ligase
- GenethrS
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids639 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- tRNA(Thr) + L-threonine + ATP = L-threonyl-tRNA(Thr) + AMP + diphosphate + H+
Cofactor
Note: Binds 1 zinc ion per subunit.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | threonine-tRNA ligase activity | |
Molecular Function | tRNA binding | |
Biological Process | threonyl-tRNA aminoacylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameThreonine--tRNA ligase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Thiomonas
Accessions
- Primary accessionD5X0W1
Subcellular Location
Interaction
Structure
Family & Domains
Features
Showing features for domain, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-61 | TGS | ||||
Sequence: MFQITLPDGSKRAFEAPLTVAELAQSIGAGLFKAALAGKVDGKLVDTSYRLSQDAEVAIVT | ||||||
Domain | 242-533 | Aminoacyl-transfer RNA synthetases class-II family profile | ||||
Sequence: DHRKLGKELDLFHFQEEAPGLAFWHPKGWALWQAVEQYMRQVYRDSGYQEVKGPQILDVSLWKRSGHWDNYSENMFFTESEKRQFAVKPMNCPGHIQIFNSGLRSYRDLPIRYGEFGSCHRNEPSGALHGLLRVRGFTQDDGHIFCTEDQIEAEVTAFHQQAMQVYTDFGFTDIALKIALRPEKRIGEEAVWDKAEAALRAALQACGVAWQELPGEGAFYGPKIEYHMKDSIGRAWQVGTMQVDFMMPERLDAEYVDEHSQRVRPVMLHRAIVGSMERFIGVLIEHYAGAMP | ||||||
Region | 242-533 | Catalytic | ||||
Sequence: DHRKLGKELDLFHFQEEAPGLAFWHPKGWALWQAVEQYMRQVYRDSGYQEVKGPQILDVSLWKRSGHWDNYSENMFFTESEKRQFAVKPMNCPGHIQIFNSGLRSYRDLPIRYGEFGSCHRNEPSGALHGLLRVRGFTQDDGHIFCTEDQIEAEVTAFHQQAMQVYTDFGFTDIALKIALRPEKRIGEEAVWDKAEAALRAALQACGVAWQELPGEGAFYGPKIEYHMKDSIGRAWQVGTMQVDFMMPERLDAEYVDEHSQRVRPVMLHRAIVGSMERFIGVLIEHYAGAMP |
Sequence similarities
Belongs to the class-II aminoacyl-tRNA synthetase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length639
- Mass (Da)72,164
- Last updated2010-07-13 v1
- ChecksumE30B42DDFFE476EF
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP002021 EMBL· GenBank· DDBJ | ADG30757.1 EMBL· GenBank· DDBJ | Genomic DNA |