D5MES8 · D5MES8_METO1
- ProteinAspartokinase
- GenelysC
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids412 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- L-aspartate + ATP = 4-phospho-L-aspartate + ADP
Pathway
Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 1/4.
Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 1/3.
Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 1/5.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 7-10 | ATP (UniProtKB | ChEBI) | |||
Binding site | 47 | substrate | |||
Binding site | 74 | substrate | |||
Binding site | 173-174 | ATP (UniProtKB | ChEBI) | |||
Binding site | 179 | ATP (UniProtKB | ChEBI) | |||
Binding site | 209-210 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | aspartate kinase activity | |
Molecular Function | ATP binding | |
Biological Process | homoserine biosynthetic process | |
Biological Process | lysine biosynthetic process via diaminopimelate | |
Biological Process | phosphorylation | |
Biological Process | threonine biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAspartokinase
- EC number
Gene names
Organism names
- Organism
- Taxonomic lineageBacteria > Candidatus Methylomirabilota > Candidatus Methylomirabilia > Candidatus Methylomirabilales > Candidatus Methylomirabilaceae > Candidatus Methylomirabilis
Accessions
- Primary accessionD5MES8
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length412
- Mass (Da)44,104
- Last updated2010-06-15 v1
- ChecksumA8C4D33C066BFD45
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
FP565575 EMBL· GenBank· DDBJ | CBE68257.1 EMBL· GenBank· DDBJ | Genomic DNA |