D5BEL8 · D5BEL8_ZUNPS
- ProteinGlutathione hydrolase proenzyme
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids570 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- an N-terminal (5-L-glutamyl)-[peptide] + an alpha-amino acid = 5-L-glutamyl amino acid + an N-terminal L-alpha-aminoacyl-[peptide]
Pathway
Sulfur metabolism; glutathione metabolism.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 106 | L-glutamate (UniProtKB | ChEBI) | |||
Active site | 379 | Nucleophile | |||
Binding site | 397-399 | L-glutamate (UniProtKB | ChEBI) | |||
Binding site | 421 | L-glutamate (UniProtKB | ChEBI) | |||
Binding site | 450-451 | L-glutamate (UniProtKB | ChEBI) | |||
Binding site | 472 | L-glutamate (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | glutathione hydrolase activity | |
Molecular Function | leukotriene C4 gamma-glutamyl transferase activity | |
Biological Process | glutathione biosynthetic process | |
Biological Process | glutathione catabolic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended nameGlutathione hydrolase proenzyme
- EC number
- Cleaved into 2 chains
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacteroidota > Flavobacteriia > Flavobacteriales > Flavobacteriaceae > Zunongwangia
Accessions
- Primary accessionD5BEL8
Proteomes
PTM/Processing
Post-translational modification
Cleaved by autocatalysis into a large and a small subunit.
Keywords
- PTM
Interaction
Subunit
This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length570
- Mass (Da)62,606
- Last updated2010-06-15 v1
- MD5 Checksum783D5BE5EC412C4DA26B83F6A9AC6A5B
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP001650 EMBL· GenBank· DDBJ | ADF55003.1 EMBL· GenBank· DDBJ | Genomic DNA |