D5B9L6 · D5B9L6_ZUNPS

Function

function

Resistance to Hg2+ in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg0.

Catalytic activity

Cofactor

FAD (UniProtKB | Rhea| CHEBI:57692 )

Note: Binds 1 FAD per subunit.

Features

Showing features for binding site.

154750100150200250300350400450500
TypeIDPosition(s)Description
Binding site128FAD (UniProtKB | ChEBI)
Binding site255-262NAD+ (UniProtKB | ChEBI)
Binding site278NAD+ (UniProtKB | ChEBI)
Binding site347NAD+ (UniProtKB | ChEBI)
Binding site388FAD (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionflavin adenine dinucleotide binding
Molecular Functionmercury (II) reductase (NADP+) activity
Molecular Functionmercury ion binding
Molecular FunctionNAD(P)H dehydrogenase (quinone) activity
Molecular FunctionNADP binding
Molecular Functionoxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
Biological Processdetoxification of mercury ion

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Mercuric reductase
  • EC number
  • Alternative names
    • Hg(II) reductase

Gene names

    • Name
      merA
    • Ordered locus names
      ZPR_4025

Organism names

Accessions

  • Primary accession
    D5B9L6

Proteomes

PTM/Processing

Features

Showing features for disulfide bond.

TypeIDPosition(s)Description
Disulfide bond119↔124Redox-active

Keywords

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain3-69HMA

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    547
  • Mass (Da)
    58,854
  • Last updated
    2010-06-15 v1
  • MD5 Checksum
    65561DF67AEB20CC919F678BE5544921
MQKEITLPIQGMTCTGCATGIEKKVKQLEGVIALDVSYPKGEGKFIFDSSTTSQQDIIDNIEMSGQYKASNGQQVSDKNNFDLIIVGGGSAAFSAAIKAESLGLKTLMVNAGLNFGGTCVNVGCVPSKNLIRAAETAYHATHSNFQGIRPKGVDIDFSQVIKDKKDLVAALQQQKYMDVVKDFKNLAMLTGWAEFVDKGTIIVDGKDTYTATNILIATGATTYIPNIEGLNEVGYLTNVSLFDLEEKPQSLTIMGAGYIGLEIAMAYNRLGVKVRIIEFTDRPLRSQTKDITDVLEAQMKKEGIEILPNFRAFKFEKQGADTIIHCNCPDGTTTQIIEKGKIVVATGTKPNTSKLGLDKIKMNLSAVGHVLVNEKMETNISNIFAAGDVTQTPPFVYTAATEGSTAVSNAFSLSKTGIDYSSLPWVVFTDPQVAGAGMDEIVAEEAGLPFEVSKLDLSHVPRALAAQDTRGFIKLIRNTETDKLIGARVIAPEGGELIQQLSMAIKFGITVKDLAESFYPYLTLGEGIKLAAITFGKDVSKLSCCAS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP001650
EMBL· GenBank· DDBJ
ADF54329.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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