D5B9D8 · D5B9D8_ZUNPS

Function

function

Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.

Catalytic activity

Cofactor

adenosylcob(III)alamin (UniProtKB | Rhea| CHEBI:18408 )

Note: Binds between the large and small subunits.

Pathway

Amine and polyamine degradation; ethanolamine degradation.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site160-162substrate
Binding site193substrate
Binding site194adenosylcob(III)alamin (UniProtKB | ChEBI)
Binding site245adenosylcob(III)alamin (UniProtKB | ChEBI)
Binding site287substrate
Binding site295adenosylcob(III)alamin (UniProtKB | ChEBI)
Binding site362substrate
Binding site401adenosylcob(III)alamin (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Cellular Componentethanolamine ammonia-lyase complex
Cellular Componentethanolamine degradation polyhedral organelle
Molecular Functioncobalamin binding
Molecular Functionethanolamine ammonia-lyase activity
Biological Processamino acid metabolic process
Biological Processethanolamine catabolic process

Keywords

  • Molecular function
    • #Lyase
  • Ligand

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Ethanolamine ammonia-lyase large subunit
  • EC number
  • Short names
    EAL large subunit

Gene names

    • Name
      eutB
    • Ordered locus names
      ZPR_1898

Organism names

Accessions

  • Primary accession
    D5B9D8

Proteomes

Subcellular Location

Interaction

Subunit

The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the EutB family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    456
  • Mass (Da)
    50,589
  • Last updated
    2010-06-15 v1
  • MD5 Checksum
    0BCCE35FD0A83662B40078FBB5C38E62
MEYKFSINNITYNFKDLKTLLAKASPERSGDVLAGIAAKDNKERVAAQYVLSDLPLKVFLENPIIPYAEDEVTRLIMNDHNAEAFYPISAFSVGEFRDWLLSYEATPTILKDISPGLAPEMVAAVSKLMRNQDLIKVAQKCEVITKFRNTLGLKDRFSVRLQPNNPIDDPKAIAASTIDGLLYGCGDAVIGINPATDSPKAVSELLKLLDNFRQQYEIPTQTCILSHITTTMEIIEKAPVDLIFQSIGGTQKANESFGINLNMLQEAYDAGLQLNRGTIGNNIMYFETGQGSELSANAHHGVDQQTCEVRAYAVARKYSPLLVNTVVGFIGPEYLYDAKQITRAALEDHFCGKMMGLPMGCDVCYTNHAEADQDDMDSLLTLLGVAGCNYIMGVPGADDVMLNYQSTSFHDAMYLRKVLNKRPAPEFEKWLLKMGIFDKQGNRQRLNESHKLISNG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP001650
EMBL· GenBank· DDBJ
ADF52223.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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