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D5ATI3 · D5ATI3_RHOCB

Function

function

NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
[2Fe-2S] cluster (UniProtKB | Rhea| CHEBI:190135 )

Note: Binds 1 [2Fe-2S] cluster per subunit.
[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

GO annotations

AspectTerm
Cellular Componentmembrane
Molecular Function2 iron, 2 sulfur cluster binding
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Functionmetal ion binding
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Molecular FunctionNADH dehydrogenase activity
Molecular Functionquinone binding
Biological ProcessATP synthesis coupled electron transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-quinone oxidoreductase
  • EC number

Gene names

    • Name
      nuoG
    • Ordered locus names
      RCAP_rcc01527

Organism names

Accessions

  • Primary accession
    D5ATI3

Proteomes

Subcellular Location

PTM/Processing

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain5-902Fe-2S ferredoxin-type
Domain90-1294Fe-4S His(Cys)3-ligated-type
Domain227-2834Fe-4S Mo/W bis-MGD-type

Sequence similarities

Belongs to the complex I 75 kDa subunit family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    665
  • Mass (Da)
    71,322
  • Last updated
    2010-06-15 v1
  • MD5 Checksum
    8A4656C8A40BAB150B53A1724CA4E401
MSTLRKIIIDGIEVEVDPSLTLIQACEQAGIEVPRFCYHERLSIAGNCRMCLVEVVGGPPKPTASCAMQIKDLRPGPNGEPSVIKTNSPMVKKAREGVMEFLLINHPLDCPICDQGGECDLQDQAMAYGGSVSRFREVKRTSDNLNLGPLVKTEMTRCISCTRCVRFTTEVAGITQMGQTGRGADSEITSYLDMTLDSNLQGNIIDLCPVGALTSKPYAFTARPWELVKTESIDVMDALGSNIRIDAKGREVKRIVPRNHDGVNEEWLSDKGRFIWDGLRRQRLDTPYIREAGKLRKASWSEALTAAAAAMTGKKVLGLIGDLCSTEAAYSLKTLIEAQGGSVECRTDGARLPIGNRSAYVGNVAIQDIDDAKEIILIGTDPRTEAPVLNARIRKAWAKGAVVRLIGPAVDLTYDYDHVGTDRAALAGLKAGKDAIVILGQGAISEADGDAVIANAMSLSGRMLMLHTAASRVGAMDVGAVTNGGLIAALEGVQVIYNMGADEVEIAPRSEGGPIVIYQGSHGDRGASRADIILPGAAYTEEHGLFVNTEGRPQLAFRATFAPGEAKENWAILRALSAELGATLPWDSLGGLRQSMLAKHPHLGDIDHLADNGWTVPERRDMGKASFRLALGDYYFTNPIARASVVMPECSAQAKGRKSPAVAAE

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP001312
EMBL· GenBank· DDBJ
ADE85272.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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