D4ZDI5 · D4ZDI5_SHEVD
- ProteinGlutathione reductase
- Genegor
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids455 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Cofactor
Note: Binds 1 FAD per subunit.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 55 | FAD (UniProtKB | ChEBI) | |||
Binding site | 119 | FAD (UniProtKB | ChEBI) | |||
Binding site | 178-185 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 266 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 307 | FAD (UniProtKB | ChEBI) | |||
Active site | 444 | Proton acceptor | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | flavin adenine dinucleotide binding | |
Molecular Function | glutathione-disulfide reductase (NADPH) activity | |
Molecular Function | NADP binding | |
Biological Process | cell redox homeostasis | |
Biological Process | cellular response to oxidative stress | |
Biological Process | glutathione metabolic process |
Keywords
- Molecular function
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Alteromonadales > Shewanellaceae > Shewanella
Accessions
- Primary accessionD4ZDI5
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for disulfide bond.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Disulfide bond | 46↔51 | Redox-active | |||
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 10-323 | FAD/NAD(P)-binding | |||
Domain | 344-454 | Pyridine nucleotide-disulphide oxidoreductase dimerisation | |||
Sequence similarities
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length455
- Mass (Da)48,904
- Last updated2010-06-15 v1
- MD5 Checksum9A658358D3B73326290B30FC90656CB5
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AP011177 EMBL· GenBank· DDBJ | BAJ00107.1 EMBL· GenBank· DDBJ | Genomic DNA |