D4ZD03 · D4ZD03_SHEVD
- ProteinSaccharopine dehydrogenase [NAD(+), L-lysine-forming]
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids367 (go to sequence)
- Protein existencePredicted
- Annotation score2/5
Function
Catalytic activity
- L-saccharopine + NAD+ + H2O = L-lysine + 2-oxoglutarate + NADH + H+
Pathway
Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-lysine from L-alpha-aminoadipate (fungal route): step 3/3.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 77 | Proton acceptor | |||
Active site | 95 | Proton donor | |||
Binding site | 129 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 205-206 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 226 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 230 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 280 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 319-322 | NAD+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | saccharopine dehydrogenase (NAD+, L-lysine-forming) activity | |
Biological Process | lysine biosynthetic process via aminoadipic acid |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSaccharopine dehydrogenase [NAD(+), L-lysine-forming]
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Alteromonadales > Shewanellaceae > Shewanella
Accessions
- Primary accessionD4ZD03
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Keywords
- PTM
Interaction
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 7-141 | Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal | |||
Domain | 181-318 | Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding | |||
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length367
- Mass (Da)40,648
- Last updated2010-06-15 v1
- MD5 Checksum6B01774A661E6F4544ECA3877749B687
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AP011177 EMBL· GenBank· DDBJ | BAJ03898.1 EMBL· GenBank· DDBJ | Genomic DNA |