D4VFV8 · D4VFV8_9BACE
- ProteinCardiolipin synthase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids479 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
Catalytic activity
- 2 a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) = a cardiolipin + glycerol
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 222 | ||||
Active site | 224 | ||||
Active site | 229 | ||||
Active site | 397 | ||||
Active site | 399 | ||||
Active site | 404 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | cardiolipin synthase activity | |
Biological Process | cardiolipin biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCardiolipin synthase
- EC number
- Short namesCL synthase
Gene names
Organism names
- Taxonomic lineageBacteria > Bacteroidota > Bacteroidia > Bacteroidales > Bacteroidaceae > Bacteroides
Accessions
- Primary accessionD4VFV8
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 12-32 | Helical | |||
Transmembrane | 44-62 | Helical | |||
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 217-244 | PLD phosphodiesterase | |||
Domain | 392-419 | PLD phosphodiesterase | |||
Sequence similarities
Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length479
- Mass (Da)55,700
- Last updated2010-06-15 v1
- MD5 Checksum921574801DCB3640A91ABD327859B1A6
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CBXG010000055 EMBL· GenBank· DDBJ | CDM07574.1 EMBL· GenBank· DDBJ | Genomic DNA |