D4QF58 · D4QF58_COTJA
- ProteinAmine oxidase
- GeneMAOA
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids148 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
Catalytic activity
- H2O + O2 + serotonin = (5-hydroxyindol-3-yl)acetaldehyde + H2O2 + NH4+
- H2O + O2 + tryptamine = H2O2 + indole-3-acetaldehyde + NH4+
- H2O + kynuramine + O2 = 3-(2-aminophenyl)-3-oxopropanal + H2O2 + NH4+This reaction proceeds in the forward direction.
Cofactor
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial outer membrane | |
Molecular Function | aliphatic amine oxidase activity | |
Molecular Function | monoamine oxidase activity | |
Molecular Function | primary amine oxidase activity | |
Biological Process | catecholamine metabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAmine oxidase
- EC number
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Galloanserae > Galliformes > Phasianidae > Perdicinae > Coturnix
Accessions
- Primary accessionD4QF58
Subcellular Location
UniProt Annotation
GO Annotation
Mitochondrion outer membrane ; Single-pass type IV membrane protein
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 2-147 | Amine oxidase | ||||
Sequence: KCMMYYKEAFWKRKGCCAALFIDDEECPIGITLDDTKPDGSFPAIMGFILTRKAVKLASLSKEERRKKICESFAKAMQMEEALHPVHYEEKNWTMEQYSGGCYTAYFPPGIMYSYGRIIRQPVDRIYFAGTETATQWSGYMEGAVQ |
Sequence similarities
Belongs to the flavin monoamine oxidase family.
Family and domain databases
Sequence
- Sequence statusFragment
- Length148
- Mass (Da)16,978
- Last updated2010-06-15 v1
- Checksum1BA58E5D40813EC2
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: I | ||||||
Non-terminal residue | 148 | |||||
Sequence: A |