D4HNR5 · D4HNR5_ORENI

Function

Catalytic activity

Cofactor

Fe2+ (UniProtKB | Rhea| CHEBI:29033 )

Pathway

Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 1/6.

Features

Showing features for binding site.

146150100150200250300350400450
TypeIDPosition(s)Description
Binding site294Fe cation (UniProtKB | ChEBI)
Binding site299Fe cation (UniProtKB | ChEBI)
Binding site339Fe cation (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functioniron ion binding
Molecular Functionphenylalanine 4-monooxygenase activity
Biological ProcessL-phenylalanine catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    phenylalanine 4-monooxygenase
  • EC number
  • Alternative names
    • Phe-4-monooxygenase

Gene names

    • Name
      Tph

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Ovalentaria > Cichlomorphae > Cichliformes > Cichlidae > African cichlids > Pseudocrenilabrinae > Oreochromini > Oreochromis

Accessions

  • Primary accession
    D4HNR5

Family & Domains

Features

Showing features for region, domain.

TypeIDPosition(s)Description
Region1-26Disordered
Domain45-123ACT
Domain115-461Biopterin-dependent aromatic amino acid hydroxylase family profile

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    461
  • Mass (Da)
    52,661
  • Last updated
    2010-05-18 v1
  • Checksum
    4E056C27F09E6D33
MDAAYKGVNGNYSPEAETGDQVPGQKRRGSMYLEEETNNKSEVISCIFSLKEEVGALAKALRLFEEKGINLTHIESRPSRMNNEQYEFFINVDSTCSQALDEVIDCLRTQISGHVHELTRSKEKDTVPWFPNDIQDLDRFANQILSYGSELDADHPGFTDPVYRARRKEFADIAYNYRHGQSIPMVEYTEEEKATWGTVFRELKTLYPTHACREHNRVFPLLEKYCGYRPDNIPQLEDVSRFLQSCTGFRLRPVAGLLSSRDFLAGLAFRVFHSTQYIRHGSKPTYTPEPDICHELLGHVPLFADPSFAQFSQEIGLASLGAPDEYIEKLATVYWFTVEFGLCKQGSEIKAYGAGLLSSFGELEYSLTEKPKLLPFDPEKTIVQKYPITEYQPVYFVAESFEDAKEKVRKFAGTIPRPFSVRYNPYTQSIEVLDNTQQLRNLADSINSEMGKLCEALRKLE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FJ800839
EMBL· GenBank· DDBJ
ACX55860.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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