D4GYG8 · AGLR_HALVD

Function

function

Involved in the assembly of a N-linked pentasaccharide that decorates the S-layer glycoprotein and flagellins. Probably mediates or contributes to the translocation of the dolichol-phosphate-mannose across the membrane.

Pathway

Cell surface structure biogenesis; S-layer biogenesis.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane
Biological ProcessS-layer organization

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Probable flippase AglR
  • Alternative names
    • Archaeal glycosylation protein R

Gene names

    • Name
      aglR
    • ORF names
      C498_02975
    • Ordered locus names
      HVO_1524

Organism names

Accessions

  • Primary accession
    D4GYG8
  • Secondary accessions
    • B7VU79

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane7-29Helical
Transmembrane34-56Helical
Transmembrane83-103Helical
Transmembrane112-132Helical
Transmembrane146-166Helical
Transmembrane168-188Helical
Transmembrane222-242Helical
Transmembrane246-266Helical
Transmembrane287-307Helical
Transmembrane310-330Helical
Transmembrane354-373Helical
Transmembrane377-396Helical
Transmembrane409-429Helical
Transmembrane439-459Helical

Keywords

Phenotypes & Variants

Disruption phenotype

Mutants show accumulation of both tetrasaccharide- and mannose-linked dolichol phosphate. The final mannose residue of the N-linked glycan decorating the S-layer glycoprotein is not added.

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004223051-476Probable flippase AglR

Proteomic databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the AglR/Agl15 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    476
  • Mass (Da)
    50,636
  • Last updated
    2010-05-18 v1
  • Checksum
    F2F4AE40E3C963AE
MAKLARASALQFGANVTQTFVGAIITIYVINELGVGAFGIFALSAALVKWASIPAVGIRGAVITRMNESDDISPSEYFTTASVLTGAIILVGLLALLGYSPFVEQYLDYSGTQLVGGMFVSNVSFRLVLGGLRGENRVEMSSLYEALWGILSSLVKLALVYTGVGVDALFYGEITSSIVIGIFGVYSLNISFVSPTRSAAISLYSWARYGWLDNLKRMSYSWLDTIILGFFVSTSLVGIYEVAWRISALFVLLPTAISKSTFPTISSLRDTDKLNKVRRILTRGLSVAGVLAIPGLVGSVLVGGDILALYGPSVSSVGVAVSVLVSLSVVRLVECYETLVMQALNALDLPDRTFRIGVIFITTNIILNVSLIPMFGVIGAAIATLLSMTLGSILAVRALPKAVQTLPPVSAIGSQFVSAGAMAVVLFTILNYRPIGQPIEVVLYVLAGATTYGFVLLSLSSNFRERVQQLLSESLG

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP001956
EMBL· GenBank· DDBJ
ADE03191.1
EMBL· GenBank· DDBJ
Genomic DNA
AOHU01000027
EMBL· GenBank· DDBJ
ELY35859.1
EMBL· GenBank· DDBJ
Genomic DNA
FM955371
EMBL· GenBank· DDBJ
CAW30729.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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