D4GYG6 · AGLQ_HALVD

Function

function

Putative isomerase involved in the N-glycosylation pathway. Required for the appearance of the methyl ester of hexuronic acid found at position four of the pentasaccharide N-linked to the S-layer glycoprotein. Either involved in preparing the third sugar for attachment of the fourth pentasaccharide subunit or processing the fourth sugar prior to its addition to the lipid-linked trisaccharide.

Pathway

Cell surface structure biogenesis; S-layer biogenesis.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Biological Processcarbohydrate metabolic process
Biological ProcessS-layer organization

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Archaeal glycosylation protein Q

Gene names

    • Name
      aglQ
    • ORF names
      C498_02965
    • Ordered locus names
      HVO_1523

Organism names

Accessions

  • Primary accession
    D4GYG6
  • Secondary accessions
    • B7VU78

Proteomes

Subcellular Location

Keywords

Phenotypes & Variants

Disruption phenotype

Defects in N-glycosylation pathway, characterized by impaired addition of the fourth sugar of the pentasaccharide: both dolichol phosphate, the lipid carrier used in H.volcanii N-glycosylation, and modified S-layer glycoprotein Asn residues only present the first three subunits of the pentasaccharide.

Features

Showing features for mutagenesis.

TypeIDPosition(s)Description
Mutagenesis34No effect.
Mutagenesis37No effect.
Mutagenesis38Defects in N-glycosylation pathway.
Mutagenesis50No effect.
Mutagenesis52Defects in N-glycosylation pathway.
Mutagenesis55No effect.
Mutagenesis58No effect.
Mutagenesis59No effect.
Mutagenesis61No effect.
Mutagenesis66No effect.
Mutagenesis81No effect.
Mutagenesis93No effect.
Mutagenesis104No effect.
Mutagenesis114No effect.
Mutagenesis118No effect.
Mutagenesis187No effect.

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004287671-371Archaeal glycosylation protein Q

Proteomic databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region19-39Disordered

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    371
  • Mass (Da)
    42,133
  • Last updated
    2010-05-18 v1
  • Checksum
    563A742EEABEF171
MTSLSDILASSAEAGLSLQRSDGSMPAGHNGPYHDPETPVRNTSHWLVTFLKAHELTDENRFRQAASDAVSYLLSEEARPHGHTFEHRQNDTKDRCNGLMGQAWSLEALALAARALDNERAAAVAADVFLSHPFCDKLKLWQRVDTDGTILGFDRTFNHQLWFAASGGLVAHTAPQEVSQRVRDFLDSLPSTIDLYENGLIRHPLRPSMDLSELAESVTHDVHRSMVRNHLLHYLRPPRSKRRLRNKAEGYHSFNLYALAILAREFPSHSVWSTDLLSDILEYTLSEEFREATTDNKFSHPYNPPGFEVPAAMETFSVGSYKEREMWVNEQIQHSFDPNTSLLTRGTDDKQTHAARLYEATRLDDYEIYLD

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FM955370
EMBL· GenBank· DDBJ
CAW30728.1
EMBL· GenBank· DDBJ
Genomic DNA
CP001956
EMBL· GenBank· DDBJ
ADE02297.1
EMBL· GenBank· DDBJ
Genomic DNA
AOHU01000027
EMBL· GenBank· DDBJ
ELY35857.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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