D4GW01 · D4GW01_HALVD
- ProteinGeranylgeranylglyceryl phosphate synthase
- GenepcrB2
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids251 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Catalytic activity
- sn-glycerol 1-phosphate + (2E,6E,10E)-geranylgeranyl diphosphate = sn-3-O-(geranylgeranyl)glycerol 1-phosphate + diphosphate
Cofactor
Pathway
Membrane lipid metabolism; glycerophospholipid metabolism.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 13 | sn-glycerol 1-phosphate (UniProtKB | ChEBI) | |||
Binding site | 15 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 38 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 183-188 | sn-glycerol 1-phosphate (UniProtKB | ChEBI) | |||
Binding site | 213 | sn-glycerol 1-phosphate (UniProtKB | ChEBI) | |||
Binding site | 234-235 | sn-glycerol 1-phosphate (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | magnesium ion binding | |
Molecular Function | phosphoglycerol geranylgeranyltransferase activity | |
Molecular Function | polyprenyltransferase activity | |
Biological Process | glycerophospholipid biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGeranylgeranylglyceryl phosphate synthase
- EC number
- Short namesGGGP synthase ; GGGPS
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageArchaea > Euryarchaeota > Stenosarchaea group > Halobacteria > Halobacteriales > Haloferacaceae > Haloferax
Accessions
- Primary accessionD4GW01
- Secondary accessions
Proteomes
Subcellular Location
PTM/Processing
Proteomic databases
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length251
- Mass (Da)27,281
- Last updated2010-05-18 v1
- Checksum8F3AD48ED8D45870
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP001956 EMBL· GenBank· DDBJ | ADE04273.1 EMBL· GenBank· DDBJ | Genomic DNA |