D4GW01 · D4GW01_HALVD

Function

function

Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Membrane lipid metabolism; glycerophospholipid metabolism.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site13sn-glycerol 1-phosphate (UniProtKB | ChEBI)
Binding site15Mg2+ (UniProtKB | ChEBI)
Binding site38Mg2+ (UniProtKB | ChEBI)
Binding site183-188sn-glycerol 1-phosphate (UniProtKB | ChEBI)
Binding site213sn-glycerol 1-phosphate (UniProtKB | ChEBI)
Binding site234-235sn-glycerol 1-phosphate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionmagnesium ion binding
Molecular Functionphosphoglycerol geranylgeranyltransferase activity
Molecular Functionpolyprenyltransferase activity
Biological Processglycerophospholipid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Geranylgeranylglyceryl phosphate synthase
  • EC number
  • Short names
    GGGP synthase
    ; GGGPS
  • Alternative names
    • (S)-3-O-geranylgeranylglyceryl phosphate synthase
    • Phosphoglycerol geranylgeranyltransferase

Gene names

    • Name
      pcrB2
    • Ordered locus names
      HVO_1086

Organism names

Accessions

  • Primary accession
    D4GW01
  • Secondary accessions
    • L9US57

Proteomes

Subcellular Location

Keywords

PTM/Processing

Proteomic databases

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the GGGP/HepGP synthase family. Group I subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    251
  • Mass (Da)
    27,281
  • Last updated
    2010-05-18 v1
  • Checksum
    8F3AD48ED8D45870
MSFDWSEFEHVTKVDPAKRHPESIDVLRHTDAVIVGGSDGVTEENSLAVFERLRAEFPDLPLVQEPYRSAHVSKRTVEVADAVFVPAVYNGDKTNFVEKHVGFFTELARKSEDVTGSGLPFVGSVLASKGRELVDGVVGEGYVVQNPDSKVAGLTNVEEHYTPEQVAGAALATESFYGFPIFYIEYSGRYVGPEDVSAAAPFLDETALLYGGGIRSRAQTDEILDAGADAVVVGDCFHEDTERFLETVPTT

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP001956
EMBL· GenBank· DDBJ
ADE04273.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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