D4GP40 · XAD_HALVD
- ProteinD-xylonate dehydratase
- GenexacD
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids412 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
function
NADP-dependent D-xylose dehydrogenase involved in the degradation of D-xylose, a major component of hemicelluloses such as xylan. Catalyzes the third reaction in the xylose utilization pathway through dehydratation of D-xylonate into 2-dehydro-3-deoxy-D-xylonate.
Catalytic activity
- D-xylonate = 2-dehydro-3-deoxy-D-arabinonate + H2O
Kinetics
KM | SUBSTRATE | pH | TEMPERATURE[C] | NOTES | EVIDENCE | |
---|---|---|---|---|---|---|
0.55 mM | xylonate | |||||
0.4 mM | gluconate |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | xylonate dehydratase activity | |
Biological Process | amino acid catabolic process |
Keywords
- Molecular function
Enzyme and pathway databases
Community annotation
Catalyzes the dehydration of xylonate to 2-dehydro-3-deoxy-D-arabinonate.
Source | Submission date | Contributor |
---|---|---|
PubMed:27297879 | ![]() |
Names & Taxonomy
Protein names
- Recommended nameD-xylonate dehydratase
- EC number
- Short namesXAD
Gene names
Community suggested name: XAD; Xylonate dehydratase; HVO_B0038A.
Source | Submission date | Contributor |
---|---|---|
PubMed:27297879 | ![]() |
Encoded on
- Plasmid pHV3
Organism names
- Strains
- Taxonomic lineageArchaea > Methanobacteriati > Methanobacteriota > Stenosarchaea group > Halobacteria > Halobacteriales > Haloferacaceae > Haloferax
Accessions
- Primary accessionD4GP40
Proteomes
Phenotypes & Variants
Disruption phenotype
Impairs growth on D-xylose as sole energy and carbon substrate.
PTM/Processing
Features
Showing features for initiator methionine, chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Initiator methionine | 1 | Removed | |||
Chain | PRO_0000428801 | 2-412 | D-xylonate dehydratase | ||
Proteomic databases
Expression
Induction
Transcriptionally up-regulated by both L-arabinose and D-xylose via the pentose-specific regulator XacR.
Interaction
Structure
Sequence
- Sequence statusComplete
- Length412
- Mass (Da)45,529
- Last updated2010-05-18 v1
- MD5 Checksum0F850E0A8D3072A450F47FC4428D5A92
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP001953 EMBL· GenBank· DDBJ | ADE01444.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AOHU01000021 EMBL· GenBank· DDBJ | ELY36793.1 EMBL· GenBank· DDBJ | Genomic DNA |