D4GP40 · XAD_HALVD

Function

function

NADP-dependent D-xylose dehydrogenase involved in the degradation of D-xylose, a major component of hemicelluloses such as xylan. Catalyzes the third reaction in the xylose utilization pathway through dehydratation of D-xylonate into 2-dehydro-3-deoxy-D-xylonate.

Catalytic activity

Kinetics

KM SUBSTRATE pH TEMPERATURE[C] NOTES EVIDENCE
0.55 mMxylonate
0.4 mMgluconate

GO annotations

AspectTerm
Molecular Functionxylonate dehydratase activity
Biological Processamino acid catabolic process

Keywords

Enzyme and pathway databases

Community curation (1)

Community annotation

Catalyzes the dehydration of xylonate to 2-dehydro-3-deoxy-D-arabinonate.

SourceSubmission dateContributor
PubMed:272978790000-0003-4691-3246

Names & Taxonomy

Protein names

  • Recommended name
    D-xylonate dehydratase
  • EC number
  • Short names
    XAD

Gene names

    • Name
      xacD
    • Synonyms
      xad
    • ORF names
      C498_01565
    • Ordered locus names
      HVO_B0038A
Community curation (1)

Community suggested name: XAD; Xylonate dehydratase; HVO_B0038A.

SourceSubmission dateContributor
PubMed:272978790000-0003-4691-3246

Encoded on

  • Plasmid pHV3

Organism names

Accessions

  • Primary accession
    D4GP40

Proteomes

Phenotypes & Variants

Disruption phenotype

Impairs growth on D-xylose as sole energy and carbon substrate.

PTM/Processing

Features

Showing features for initiator methionine, chain.

Type
IDPosition(s)Description
Initiator methionine1Removed
ChainPRO_00004288012-412D-xylonate dehydratase

Proteomic databases

Expression

Induction

Transcriptionally up-regulated by both L-arabinose and D-xylose via the pentose-specific regulator XacR.

Interaction

Subunit

Homooctamer.

Protein-protein interaction databases

Structure

Family & Domains

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    412
  • Mass (Da)
    45,529
  • Last updated
    2010-05-18 v1
  • MD5 Checksum
    0F850E0A8D3072A450F47FC4428D5A92
MVEQAKLSDPNAEYTMRDLSAETIDITNPRGGVRDAEITDVQTTMVDGNYPWILVRVYTDAGVVGTGEAYWGGGDTAIIERMKPFLVGENPLDIDRLYEHLVQKMSGEGSVSGKVISAISGIEIALHDVAGKLLDVPAYQLVGGKYRDEVRVYCDLHTEDEANPQACAEEGVRVVEELGYDAIKFDLDVPSGHEKDRANRHLRNPEIDHKVEIVEAVTEAVGDRADVAFDCHWSFTGGSAKRLASELEDYDVWWLEDPVPPENHDVQKLVTQSTTTPIAVGENVYRKFGQRTLLEPQAVDIIAPDLPRVGGMRETRKIADLADMYYIPVAMHNVSSPIGTMASAQVAAAIPNSLALEYHSYQLGWWEDLVEEDDLIQNGHMEIPEKPGLGLTLDLDAVEAHMVEGETLFDEE

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP001953
EMBL· GenBank· DDBJ
ADE01444.1
EMBL· GenBank· DDBJ
Genomic DNA
AOHU01000021
EMBL· GenBank· DDBJ
ELY36793.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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