D4B5F9 · PGDA_ARTBC

Function

function

Catalyzes the deacetylation of N-acetylglucosamine (GlcNAc) residues in peptidoglycan.

Catalytic activity

  • peptidoglycan-N-acetyl-D-glucosamine + H2O = peptidoglycan-D-glucosamine + acetate.
    EC:3.5.1.104 (UniProtKB | ENZYME | Rhea)

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Co2+ (UniProtKB | Rhea| CHEBI:48828 )

Features

Showing features for active site, binding site, site.

143750100150200250300350400
TypeIDPosition(s)Description
Active site156Proton acceptor
Binding site157Zn2+ (UniProtKB | ChEBI)
Binding site209Zn2+ (UniProtKB | ChEBI)
Binding site213Zn2+ (UniProtKB | ChEBI)
Binding site251substrate
Site278Raises pKa of active site His
Active site308Proton donor

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentextracellular region
Molecular Functionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
Molecular Functionmetal ion binding
Biological Processcarbohydrate metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Probable peptidoglycan-N-acetylglucosamine deacetylase ARB_03699
  • EC number
  • Short names
    Peptidoglycan GlcNAc deacetylase
  • Alternative names
    • Peptidoglycan N-deacetylase
      (PG N-deacetylase
      )

Gene names

    • ORF names
      ARB_03699

Organism names

Accessions

  • Primary accession
    D4B5F9

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, chain, glycosylation.

TypeIDPosition(s)Description
Signal1-20
ChainPRO_500305470221-437Probable peptidoglycan-N-acetylglucosamine deacetylase ARB_03699
Glycosylation99N-linked (GlcNAc...) asparagine

Keywords

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region, domain, compositional bias.

TypeIDPosition(s)Description
Region47-132Disordered
Domain149-334NodB homology
Compositional bias350-367Polar residues
Region350-384Disordered
Domain389-435LysM

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    437
  • Mass (Da)
    45,972
  • Last updated
    2015-12-09 v2
  • Checksum
    3C3118F6722B3EC9
MLMRLYTFFAAALLACCAAAGPLHPELPQLVGKSWIPDWWFPFPRPSTRAATTTTTPATSTTGLATTTTKPTTTSSKPVTPTPQPATSTAQPAISSTANATATATASSASTSTTSSSTSASTSTSAAAPSTPTTVVPFGQVIRSCTVKGTVAITFDDGPYDYTNKLLDIFDANGAKATLFVNAQNFGSITDYSSVMLRAFNTGHQIASHTYDHADLSTLNGAGIISEMTKLDDVLATITNGYRPTYMRVPYFAYSPLVLQTMADLKYHVIEADIDTKDYEHDTPDGVSVSVGFFRDGLNAGGSIALAHDVHQTTVDLLIQQLLDEVKRRGLKAVTVGECLGDPRANWYRTTPVQVPTGTSTTSPTATPTSPGTPPPAPTQPGVASNCQKWHTVVSGDTCYDIAAANGISLDNLYKWNPAVGTSCASLWLGYAVCVGV

Sequence caution

The sequence EFE29445.1 differs from that shown. Reason: Erroneous gene model prediction

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias350-367Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
ABSU01000040
EMBL· GenBank· DDBJ
EFE29445.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.

Genome annotation databases

Similar Proteins

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