Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.Rush J., Moritz A., Lee K.A., Guo A., Goss V.L., Spek E.J., Zhang H., Zha X.-M., Polakiewicz R.D., Comb M.J.View abstractCited forIDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]CategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCNat. Biotechnol. 23:94-101 (2005)Cited in99+99+Mapped to4
The phagosomal proteome in interferon-gamma-activated macrophages.Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P.View abstractCited forIDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]CategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCImmunity 30:143-154 (2009)Cited in99+99+Mapped to99+
Lineage-specific biology revealed by a finished genome assembly of the mouse.Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L.[...], Ponting C.P.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol. 7:E1000112-E1000112 (2009)Cited in99+99+
A tissue-specific atlas of mouse protein phosphorylation and expression.Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R., Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.View abstractCited forIDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]CategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCCell 143:1174-1189 (2010)Cited in99+99+Mapped to6
Modernizing reference genome assemblies.Church D.M., Schneider V.A., Graves T., Auger K., Cunningham F., Bouk N., Chen H.C., Agarwala R., McLaren W.M.[...], Hubbard T.Cited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol 9:e1001091-e1001091 (2011)Cited in99+
SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.Park J., Chen Y., Tishkoff D.X., Peng C., Tan M., Dai L., Xie Z., Zhang Y., Zwaans B.M.[...], Zhao Y.View abstractCited forIDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]CategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCMol. Cell 50:919-930 (2013)Cited in99+99+Mapped to6
No title available.EnsemblCited forIDENTIFICATIONStrainC57BL/6JSourceUniProtKB unreviewed (TrEMBL)Submission Submitted to UniProtKB (JUN-2024)Cited in99+
Gads is a novel SH2 and SH3 domain-containing adaptor protein that binds to tyrosine-phosphorylated Shc.Liu S.K., McGlade C.J.View abstractCategoriesInteractionSourceMGI: 98296PubMedEurope PMCOncogene 17:3073-3082 (1998)Cited in1Mapped to20
The 66-kDa Shc isoform is a negative regulator of the epidermal growth factor-stimulated mitogen-activated protein kinase pathway.Okada S., Kao A.W., Ceresa B.P., Blaikie P., Margolis B., Pessin J.E.View abstractCategoriesSequencesSourceMGI: 98296PubMedEurope PMCJ Biol Chem 272:28042-28049 (1997)Mapped to5
Shc contains two Grb2 binding sites needed for efficient formation of complexes with SOS in B lymphocytes.Harmer S.L., DeFranco A.L.View abstractCategoriesPTM / Processing, InteractionSourceMGI: 98296PubMedEurope PMCMol Cell Biol 17:4087-4095 (1997)Mapped to99+
Opposite effects of the p52shc/p46shc and p66shc splicing isoforms on the EGF receptor-MAP kinase-fos signalling pathway.Migliaccio E., Mele S., Salcini A.E., Pelicci G., Lai K.M., Superti-Furga G., Pawson T., Di Fiore P.P., Lanfrancone L., Pelicci P.-G.View abstractCategoriesSequencesSourceMGI: 98296PubMedEurope PMCEMBO J. 16:706-716 (1997)Cited in1Mapped to5
Cripto enhances the tyrosine phosphorylation of Shc and activates mitogen- activated protein kinase (MAPK) in mammary epithelial cells.Kannan S., De Santis M., Lohmeyer M., Riese D.J., Smith G.H., Hynes N., Seno M., Brandt R., Bianco C.[...], Salomon D.S.View abstractCategoriesFunctionSourceMGI: 98296PubMedEurope PMCJ Biol Chem 272:3330-3335 (1997)Mapped to17
The Grb2-mSos1 complex binds phosphopeptides with higher affinity than Grb2.Chook Y.M., Gish G.D., Kay C.M., Pai E.F., Pawson T.View abstractCategoriesInteractionSourceMGI: 98296PubMedEurope PMCJ Biol Chem 271:30472-30478 (1996)Mapped to21
The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein.Borg J.-P., Ooi J., Levy E., Margolis B.View abstractCategoriesInteractionSourceMGI: 98296PubMedEurope PMCMol. Cell. Biol. 16:6229-6241 (1996)Cited in2Mapped to9
Evidence for the direct interaction of the insulin-like growth factor I receptor with IRS-1, Shc, and Grb10.Dey B.R., Frick K., Lopaczynski W., Nissley S.P., Furlanetto R.W.View abstractCategoriesInteractionSourceMGI: 98296PubMedEurope PMCMol Endocrinol 10:631-641 (1996)Mapped to11
A mammalian adaptor protein with conserved Src homology 2 and phosphotyrosine-binding domains is related to Shc and is specifically expressed in the brain.O'Bryan J.P., Songyang Z., Cantley L., Der C.J., Pawson T.View abstractCategoriesInteractionSourceMGI: 98296PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 93:2729-2734 (1996)Cited in1Mapped to22
The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1.Rozakis-Adcock M., Fernley R., Wade J., Pawson T., Bowtell D.View abstractCategoriesFunctionSourceMGI: 98296PubMedEurope PMCNature 363:83-85 (1993)Mapped to19
Shc products are substrates of erbB-2 kinase.Segatto O., Pelicci G., Giuli S., Digiesi G., Di Fiore P.P., McGlade J., Pawson T., Pelicci P.G.View abstractCategoriesInteractionSourceMGI: 98296PubMedEurope PMCOncogene 8:2105-2112 (1993)Mapped to22
A dominant-negative mutant of mSOS1 inhibits insulin-induced Ras activation and reveals Ras-dependent and -independent insulin signaling pathways.Sakaue M., Bowtell D., Kasuga M.View abstractCategoriesFunctionSourceMGI: 98296PubMedEurope PMCMol Cell Biol 15:379-388 (1995)Mapped to11
A region in Shc distinct from the SH2 domain can bind tyrosine- phosphorylated growth factor receptors.Blaikie P.A., Immanuel D., Wu J., Li N., Yajnik V., Margolis B.View abstractCategoriesInteractionSourceMGI: 98296PubMedEurope PMCJ. Biol. Chem. 269:32031-32034 (1994)Cited in1Mapped to10
Molecular cloning of the mouse grb2 gene: differential interaction of the Grb2 adaptor protein with epidermal growth factor and nerve growth factor receptors.Suen K., Bustelo X.R., Pawson T., Barbacid M.View abstractCategoriesSequences, InteractionSourceMGI: 98296PubMedEurope PMCMol. Cell. Biol. 13:5500-5512 (1993)Cited in1Mapped to29
Tyrosine phosphorylation of the c-cbl proto-oncogene protein product and association with epidermal growth factor (EGF) receptor upon EGF stimulation.Galisteo M.L., Dikic I., Batzer A.G., Langdon W.Y., Schlessinger J.View abstractCategoriesFunction, InteractionSourceMGI: 98296PubMedEurope PMCJ. Biol. Chem. 270:20242-20245 (1995)Cited in2Mapped to32
Growth hormone-promoted tyrosyl phosphorylation of SHC proteins and SHC association with Grb2.VanderKuur J., Allevato G., Billestrup N., Norstedt G., Carter-Su C.View abstractCategoriesInteractionSourceMGI: 98296PubMedEurope PMCJ Biol Chem 270:7587-7593 (1995)Mapped to24
Interaction of Shc with Grb2 regulates association of Grb2 with mSOS.Ravichandran K.S., Lorenz U., Shoelson S.E., Burakoff S.J.View abstractCategoriesInteractionSourceMGI: 98296PubMedEurope PMCMol Cell Biol 15:593-600 (1995)Mapped to10
p66Shc deficiency in CLL cells enhances PD-L1 expression and suppresses immune synapse formation.Lopresti L., Capitani N., Tatangelo V., Tangredi C., Boncompagni G., Frezzato F., Visentin A., Marotta G., Ciofini S.[...], Patrussi L.View abstractSourceMGI: 98296PubMedEurope PMCFront Cell Dev Biol 12:1297116-1297116 (2024)Mapped to5