Lineage-specific biology revealed by a finished genome assembly of the mouse.Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L.[...], Ponting C.P.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategorySequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol. 7:E1000112-E1000112 (2009)Cited in99+99+
Modernizing reference genome assemblies.Church D.M., Schneider V.A., Graves T., Auger K., Cunningham F., Bouk N., Chen H.C., Agarwala R., McLaren W.M.[...], Hubbard T.Cited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategorySequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol 9:e1001091-e1001091 (2011)Cited in99+
No title available.EnsemblCited forIDENTIFICATIONStrainC57BL/6JSourceUniProtKB unreviewed (TrEMBL)Submission Submitted to UniProtKB (AUG-2024)Cited in99+
Major histocompatibility complex class I- and II-deficient knock-out mice are resistant to primary but susceptible to secondary Eimeria papillata infections.Schito M.L., Chobotar B., Barta J.R.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1196377PubMedEurope PMCParasitol Res 84:394-398 (1998)Mapped to40
Lymphoid expression and regulation of A20, an inhibitor of programmed cell death.Tewari M., Wolf F.W., Seldin M.F., O'Shea K.S., Dixit V.M., Turka L.A.View abstractCategoriesSequences, ExpressionSourceMGI: 1196377PubMedEurope PMCJ. Immunol. 154:1699-1706 (1995)Cited in1Mapped to15
Retinoid orphan receptor gamma t (rorgammat) promotes inflammatory eosinophilia but is dispensable for innate immune-mediated colitis.Torres-Huerta A., Ruley-Haase K., Reed T., Boger-May A., Rubadeux D., Mayer L., Rajashekara A.M., Hiller M., Frech M.[...], Boone D.L.View abstractCategoryFunctionSourceMGI: 1196377PubMedEurope PMCPLoS One 19:e0300892-e0300892 (2024)Mapped to16
Inflammasome signaling is dispensable for ss-amyloid-induced neuropathology in preclinical models of Alzheimer's disease.Srinivasan S., Kancheva D., De Ren S., Saito T., Jans M., Boone F., Vandendriessche C., Paesmans I., Maurin H.[...], van Loo G.View abstractCategoryFunctionSourceMGI: 1196377PubMedEurope PMCFront Immunol 15:1323409-1323409 (2024)Mapped to28
Protein citrullination and NET formation do not contribute to the pathology of A20/TNFAIP3 mutant mice.Van Damme K.F.A., Hertens P., Martens A., Gilis E., Priem D., Bruggeman I., Fossoul A., Declercq J., Aegerter H.[...], van Loo G.View abstractCategoryFunctionSourceMGI: 1196377PubMedEurope PMCSci Rep 13:17992-17992 (2023)Mapped to11
Obesity-associated microglial inflammatory activation paradoxically improves glucose tolerance.Douglass J.D., Ness K.M., Valdearcos M., Wyse-Jackson A., Dorfman M.D., Frey J.M., Fasnacht R.D., Santiago O.D., Niraula A.[...], Thaler J.P.View abstractCategoryFunctionSourceMGI: 1196377PubMedEurope PMCCell Metab 35:1613-1629.e8 (2023)Mapped to24
A20 is a master switch of IL-33 signaling in macrophages and determines IL-33-induced lung immunity.Holgado A., Liu Z., Aidarova A., Mueller C., Haegman M., Driege Y., Kreike M., Scott C.L., Afonina I.S., Beyaert R.View abstractCategoryFunctionSourceMGI: 1196377PubMedEurope PMCJ Allergy Clin Immunol 152:244-256.e4 (2023)Mapped to16
A20 and the noncanonical NF-kappaB pathway are key regulators of neutrophil recruitment during fetal ontogeny.Rohwedder I., Wackerbarth L.M., Heinig K., Ballweg A., Altstatter J., Ripphahn M., Nussbaum C., Salvermoser M., Bierschenk S.[...], Sperandio M.View abstractCategoriesFunction, ExpressionSourceMGI: 1196377PubMedEurope PMCJCI Insight 8:e155968-e155968 (2023)Mapped to27
Fibroblast A20 governs fibrosis susceptibility and its repression by DREAM promotes fibrosis in multiple organs.Wang W., Bale S., Wei J., Yalavarthi B., Bhattacharyya D., Yan J.J., Abdala-Valencia H., Xu D., Sun H.[...], Varga J.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1196377PubMedEurope PMCNat Commun 13:6358-6358 (2022)Mapped to16
A20 (Tnfaip3) expressed in CD4<sup>+</sup> T cells suppresses Th2 cell- mediated allergic airway inflammation in mice.Yokoyama Y., Tamachi T., Iwata A., Maezawa Y., Meguro K., Yokota M., Takatori H., Suto A., Suzuki K.[...], Nakajima H.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1196377PubMedEurope PMCBiochem Biophys Res Commun 629:47-53 (2022)Mapped to8
TNFAIP3 is anti-inflammatory in the retinal vasculature.Liu L., Jiang Y., Steinle J.J.View abstractCategoryFunctionSourceMGI: 1196377PubMedEurope PMCMol Vis 28:124-129 (2022)Mapped to21
<i>Leishmania guyanensis</i> suppressed inducible nitric oxide synthase provoked by its viral endosymbiont.Kopelyanskiy D., Desponds C., Prevel F., Rossi M., Migliorini R., Snaka T., Eren R.O., Claudinot S., Lye L.F.[...], Fasel N.View abstractSourceMGI: 1196377PubMedEurope PMCFront Cell Infect Microbiol 12:944819-944819 (2022)Mapped to35
STAT3 regulates inflammatory cytokine production downstream of TNFR1 by inducing expression of TNFAIP3/A20.Antonia R.J., Karelehto E., Toriguchi K., Matli M., Warren R.S., Pfeffer L.M., Donner D.B.View abstractCategoryFunctionSourceMGI: 1196377PubMedEurope PMCJ Cell Mol Med 26:4591-4601 (2022)Mapped to26
A SOX17-PDGFB signaling axis regulates aortic root development.Lu P., Wang P., Wu B., Wang Y., Liu Y., Cheng W., Feng X., Yuan X., Atteya M.M.[...], Zhou B.View abstractCategoryFunctionSourceMGI: 1196377PubMedEurope PMCNat Commun 13:4065-4065 (2022)Mapped to99+
Intestinal inflammation alters the antigen-specific immune response to a skin commensal.Merana G.R., Dwyer L.R., Dhariwala M.O., Weckel A., Gonzalez J.R., Okoro J.N., Cohen J.N., Tamaki C.M., Han J.[...], Scharschmidt T.C.View abstractSourceMGI: 1196377PubMedEurope PMCCell Rep 39:110891-110891 (2022)Mapped to30
TNFAIP3 may be key to TLR4-activation of the inflammasome in the retinal vasculature.Liu L., Jiang Y., Steinle J.J.View abstractCategoryFunctionSourceMGI: 1196377PubMedEurope PMCExp Eye Res 220:109108-109108 (2022)Mapped to15
TNFAIP3 Reduction-of-Function Drives Female Infertility and CNS Inflammation.Zammit N.W., McDowell J., Warren J., Muskovic W., Gamble J., Shi Y.C., Kaczorowski D., Chan C.L., Powell J.[...], Grey S.T.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1196377PubMedEurope PMCFront Immunol 13:811525-811525 (2022)Mapped to26
Microbial signals, MyD88, and lymphotoxin drive TNF-independent intestinal epithelial tissue damage.Rusu I., Mennillo E., Bain J.L., Li Z., Sun X., Ly K.M., Rosli Y.Y., Naser M., Wang Z.[...], Kattah M.G.View abstractCategoryFunctionSourceMGI: 1196377PubMedEurope PMCJ Clin Invest 132:e154993-e154993 (2022)Mapped to36
Nickel particles are present in Crohn's disease tissue and exacerbate intestinal inflammation in IBD susceptible mice.Matsuda H., Nibe-Shirakihara Y., Tamura A., Aonuma E., Arakawa S., Otsubo K., Nemoto Y., Nagaishi T., Tsuchiya K.[...], Oshima S.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1196377PubMedEurope PMCBiochem Biophys Res Commun 592:74-80 (2022)Mapped to13
A20 deficiency in myeloid cells protects mice from diet-induced obesity and insulin resistance due to increased fatty acid metabolism.Catrysse L., Maes B., Mehrotra P., Martens A., Hoste E., Martens L., Maueroder C., Remmerie A., Bujko A.[...], van Loo G.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1196377PubMedEurope PMCCell Rep 36:109748-109748 (2021)Mapped to31
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.Bedogni F., Hevner R.F.View abstractCategoryFunctionSourceMGI: 1196377PubMedEurope PMCFront Mol Neurosci 14:686034-686034 (2021)Mapped to99+
A20 functions as a negative regulator in macrophage for DSS-induced colitis.Pu T., Liu W., Wu Y., Zhao Y.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1196377PubMedEurope PMCInt Immunopharmacol 97:107804-107804 (2021)Mapped to19