The phagosomal proteome in interferon-gamma-activated macrophages.Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P.View abstractCited forIDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]CategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCImmunity 30:143-154 (2009)Cited in99+99+Mapped to99+
Lineage-specific biology revealed by a finished genome assembly of the mouse.Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L.[...], Ponting C.P.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol. 7:E1000112-E1000112 (2009)Cited in99+99+
Modernizing reference genome assemblies.Church D.M., Schneider V.A., Graves T., Auger K., Cunningham F., Bouk N., Chen H.C., Agarwala R., McLaren W.M.[...], Hubbard T.Cited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol 9:e1001091-e1001091 (2011)Cited in99+
No title available.EnsemblCited forIDENTIFICATIONStrainC57BL/6JSourceUniProtKB unreviewed (TrEMBL)Submission Submitted to UniProtKB (JUN-2024)Cited in99+
TMEM106B coding variant is protective and deletion detrimental in a mouse model of tauopathy.Edwards G.A., Wood C.A., He Y., Nguyen Q., Kim P.J., Gomez-Gutierrez R., Park K.W., Xu Y., Zurhellen C.[...], Jankowsky J.L.View abstractSourceMGI: 1919150PubMedEurope PMCActa Neuropathol 147:61-61 (2024)Mapped to6
Genetic determinants of micronucleus formation in vivo.Adams D.J., Barlas B., McIntyre R.E., Salguero I., van der Weyden L., Barros A., Vicente J.R., Karimpour N., Haider A.[...], White J.K.View abstractSourceMGI: 1919150PubMedEurope PMCNature 627:130-136 (2024)Mapped to99+
The TMEM106B T186S coding variant increases neurite arborization and synaptic density in primary hippocampal neurons.Nguyen Q., Wood C.A., Kim P.J., Jankowsky J.L.View abstractCategoriesFunctionSourceMGI: 1919150PubMedEurope PMCFront Neurosci 17:1275959-1275959 (2023)Mapped to6
AAV-<i>GRN</i> partially corrects motor deficits and ALS/FTLD-related pathology in <i>Tmem106b</i><sup><i>-/-</i></sup><i>Grn</i><sup><i>-/-</i></sup> mice.Feng T., Minevich G., Liu P., Qin H.X., Wozniak G., Pham J., Pham K., Korgaonkar A., Kurnellas M.[...], Hu F.View abstractSourceMGI: 1919150PubMedEurope PMCiScience 26:107247-107247 (2023)Mapped to23
TMEM106B Puncta Is Increased in Multiple Sclerosis Plaques, and Reduced Protein in Mice Results in Delayed Lipid Clearance Following CNS Injury.Shafit-Zagardo B., Sidoli S., Goldman J.E., DuBois J.C., Corboy J.R., Strittmatter S.M., Guzik H., Edema U., Arackal A.G.[...], Graff S.View abstractCategoriesFunctionSourceMGI: 1919150PubMedEurope PMCCells 12:1734-1734 (2023)Mapped to5
TMEM106B is a receptor mediating ACE2-independent SARS-CoV-2 cell entry.Baggen J., Jacquemyn M., Persoons L., Vanstreels E., Pye V.E., Wrobel A.G., Calvaresi V., Martin S.R., Roustan C.[...], Daelemans D.View abstractSourceMGI: 1919150PubMedEurope PMCCell 186:1-16 (2023)Cited in2Mapped to11
TMEM106B regulates microglial proliferation and survival in response to demyelination.Zhang T., Pang W., Feng T., Guo J., Wu K., Nunez Santos M., Arthanarisami A., Nana A.L., Nguyen Q.[...], Hu F.View abstractCategoriesFunctionSourceMGI: 1919150PubMedEurope PMCSci Adv 9:eadd2676-eadd2676 (2023)Mapped to9
Lack of a protective effect of the Tmem106b "protective SNP" in the Grn knockout mouse model for frontotemporal lobar degeneration.Cabron A.S., Borgmeyer U., Richter J., Peisker H., Gutbrod K., Dormann P., Capell A., Damme M.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1919150PubMedEurope PMCActa Neuropathol Commun 11:21-21 (2023)Mapped to23
TMEM106B deficiency impairs cerebellar myelination and synaptic integrity with Purkinje cell loss.Feng T., Luan L., Katz I.I., Ullah M., Van Deerlin V.M., Trojanowski J.Q., Lee E.B., Hu F.View abstractCategoriesFunction, Expression, Phenotypes & VariantsSourceMGI: 1919150PubMedEurope PMCActa Neuropathol Commun 10:33-33 (2022)Mapped to5
Spreading of Alzheimer tau seeds is enhanced by aging and template matching with limited impact of amyloid-beta.Nies S.H., Takahashi H., Herber C.S., Huttner A., Chase A., Strittmatter S.M.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1919150PubMedEurope PMCJ Biol Chem 297:101159-101159 (2021)Mapped to80
Fronto-temporal dementia risk gene <i>TMEM106B</i> has opposing effects in different lysosomal storage disorders.Perez-Canamas A., Takahashi H., Lindborg J.A., Strittmatter S.M.View abstractCategoriesFunctionSourceMGI: 1919150PubMedEurope PMCBrain Commun 3:fcaa200-fcaa200 (2021)Mapped to34
Loss of TMEM106B potentiates lysosomal and FTLD-like pathology in progranulin-deficient mice.Werner G., Damme M., Schludi M., Gnoerich J., Wind K., Fellerer K., Wefers B., Wurst W., Edbauer D.[...], Capell A.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1919150PubMedEurope PMCEMBO Rep. 21:e50241-e50241 (2020)Cited in2Mapped to21
Loss of TMEM106B and PGRN leads to severe lysosomal abnormalities and neurodegeneration in mice.Feng T., Mai S., Roscoe J.M., Sheng R.R., Ullah M., Zhang J., Katz I.I., Yu H., Xiong W., Hu F.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1919150PubMedEurope PMCEMBO Rep. 21:e50219-e50219 (2020)Cited in2Mapped to21
Loss of Tmem106b exacerbates FTLD pathologies and causes motor deficits in progranulin-deficient mice.Zhou X., Brooks M., Jiang P., Koga S., Zuberi A.R., Baker M.C., Parsons T.M., Castanedes-Casey M., Phillips V.[...], Rademakers R.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1919150PubMedEurope PMCEMBO Rep. 21:e50197-e50197 (2020)Cited in2Mapped to21
A role of the frontotemporal lobar degeneration risk factor TMEM106B in myelination.Feng T., Sheng R.R., Sole-Domenech S., Ullah M., Zhou X., Mendoza C.S., Enriquez L.C.M., Katz I.I., Paushter D.H.[...], Hu F.View abstractSourceMGI: 1919150PubMedEurope PMCBrain 143:2255-2271 (2020)Mapped to9
Loss of TMEM106B leads to myelination deficits: implications for frontotemporal dementia treatment strategies.Zhou X., Nicholson A.M., Ren Y., Brooks M., Jiang P., Zuberi A., Phuoc H.N., Perkerson R.B., Matchett B.[...], Rademakers R.View abstractCategoriesFunctionSourceMGI: 1919150PubMedEurope PMCBrain 143:1905-1919 (2020)Mapped to9
The FTLD risk factor TMEM106B regulates the transport of lysosomes at the axon initial segment of motoneurons.Lueningschroer P., Werner G., Stroobants S., Kakuta S., Dombert B., Sinske D., Wanner R., Luellmann-Rauch R., Wefers B.[...], Damme M.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1919150PubMedEurope PMCCell Rep. 30:3506-3519 (2020)Cited in1Mapped to4
Frontotemporal dementia causative CHMP2B impairs neuronal endolysosomal traffic-rescue by TMEM106B knockdown.Clayton E.L., Milioto C., Muralidharan B., Norona F.E., Edgar J.R., Soriano A., Jafar-Nejad P., Rigo F., Collinge J., Isaacs A.M.View abstractCategoriesFunction, Subcellular LocationSourceMGI: 1919150PubMedEurope PMCBrain 141:3428-3442 (2018)Mapped to7
Partial Tmem106b reduction does not correct abnormalities due to progranulin haploinsufficiency.Arrant A.E., Nicholson A.M., Zhou X., Rademakers R., Roberson E.D.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1919150PubMedEurope PMCMol Neurodegener 13:32-32 (2018)Mapped to23
Loss of Tmem106b is unable to ameliorate frontotemporal dementia-like phenotypes in an AAV mouse model of C9ORF72-repeat induced toxicity.Nicholson A.M., Zhou X., Perkerson R.B., Parsons T.M., Chew J., Brooks M., DeJesus-Hernandez M., Finch N.A., Matchett B.J.[...], Rademakers R.View abstractCategoriesFunction, InteractionSourceMGI: 1919150PubMedEurope PMCActa Neuropathol. Commun. 6:42-42 (2018)Cited in1Mapped to4
Loss of TMEM106B ameliorates lysosomal and frontotemporal dementia-related phenotypes in progranulin-deficient mice.Klein Z.A., Takahashi H., Ma M., Stagi M., Zhou M., Lam T.T., Strittmatter S.M.View abstractCategoriesFunctionSourceMGI: 1919150PubMedEurope PMCNeuron 95:281-296 (2017)Cited in4Mapped to41