D3YUE8 · D3YUE8_MOUSE

  • Protein
    Phosphoglycerate mutase
  • Gene
    Bpgm
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    3/5

Function

function

Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3-bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.11) activity.

Catalytic activity

Features

Showing features for binding site, active site.

1132102030405060708090100110120130
TypeIDPosition(s)Description
Binding site10-17substrate
Active site11Tele-phosphohistidine intermediate
Binding site62substrate
Active site89Proton donor/acceptor
Binding site89-92substrate
Binding site116-117substrate

GO annotations

AspectTerm
Molecular Function2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity
Molecular Functionbisphosphoglycerate mutase activity
Biological Processglycolytic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

Gene names

    • Name
      Bpgm

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • C57BL/6J
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    D3YUE8

Proteomes

Organism-specific databases

PTM/Processing

Expression

Gene expression databases

Interaction

Subunit

Homodimer.

Structure

Family & Domains

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    132
  • Mass (Da)
    15,665
  • Last updated
    2010-04-20 v1
  • Checksum
    39494B776B1D5CFA
MSKHKLIILRHGEGQWNKENRFCSWVDQKLNNDGLEEARNCGRQLKALNFEFDLVFTSILNRSIHTAWLILEELGQEWVPVESSWRLNERHYGALIGLNREKMALNHGEEQVRLWRRSYNVTPPPIEESHPY

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
P15327PMGE_MOUSEBpgm259
D3YYH3D3YYH3_MOUSEBpgm112
D3Z223D3Z223_MOUSEBpgm166

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue132

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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