D3YUE8 · D3YUE8_MOUSE
- ProteinPhosphoglycerate mutase
- GeneBpgm
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids132 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3-bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.11) activity.
Catalytic activity
- (2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 10-17 | substrate | ||||
Sequence: RHGEGQWN | ||||||
Active site | 11 | Tele-phosphohistidine intermediate | ||||
Sequence: H | ||||||
Binding site | 62 | substrate | ||||
Sequence: R | ||||||
Active site | 89 | Proton donor/acceptor | ||||
Sequence: E | ||||||
Binding site | 89-92 | substrate | ||||
Sequence: ERHY | ||||||
Binding site | 116-117 | substrate | ||||
Sequence: RR |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity | |
Molecular Function | bisphosphoglycerate mutase activity | |
Biological Process | glycolytic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhosphoglycerate mutase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionD3YUE8
Proteomes
Organism-specific databases
PTM/Processing
Proteomic databases
Expression
Gene expression databases
Interaction
Subunit
Homodimer.
Structure
Sequence
- Sequence statusFragment
- Length132
- Mass (Da)15,665
- Last updated2010-04-20 v1
- Checksum39494B776B1D5CFA
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 132 | |||||
Sequence: Y |
Keywords
- Technical term