D3VY07 · D3VY07_9CNID

Function

function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmembrane
Cellular Componentmitochondrion
Molecular FunctionNADH dehydrogenase (ubiquinone) activity

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH:ubiquinone reductase (H(+)-translocating)
  • EC number

Gene names

    • Name
      ND2

Encoded on

  • Mitochondrion

Organism names

Accessions

  • Primary accession
    D3VY07

Subcellular Location

Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane6-26Helical
Transmembrane33-51Helical
Transmembrane57-77Helical
Transmembrane89-113Helical
Transmembrane140-162Helical

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain10-100NADH dehydrogenase subunit 2 N-terminal
Domain103-173NADH:quinone oxidoreductase/Mrp antiporter membrane subunit

Sequence similarities

Belongs to the complex I subunit 2 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    188
  • Mass (Da)
    20,456
  • Last updated
    2010-04-20 v1
  • Checksum
    F2D7BA8A4BC2FD29
MWVHSPWHPMELTLGLIILIVLMYGLKAPTLRLAIFCLGVTLLMGAAGLLAEPHLLCWTQAIKMLVMLSGLAILCMLDHRTSHQSSSLLILLVILGNLLLIGSTNLILIYLALEMQTLCMFILVAYNKNSLLSAEAGLKYFVLGALSSGLFLFGCALIYGSTGELELQFIRMSIISYGALAGKCLITI

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue188

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
GQ293330
EMBL· GenBank· DDBJ
ADC97822.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128447
EMBL· GenBank· DDBJ
AFP28837.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128450
EMBL· GenBank· DDBJ
AFP28840.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128452
EMBL· GenBank· DDBJ
AFP28842.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128453
EMBL· GenBank· DDBJ
AFP28843.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128454
EMBL· GenBank· DDBJ
AFP28844.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128456
EMBL· GenBank· DDBJ
AFP28846.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128458
EMBL· GenBank· DDBJ
AFP28848.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128460
EMBL· GenBank· DDBJ
AFP28850.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128461
EMBL· GenBank· DDBJ
AFP28851.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128463
EMBL· GenBank· DDBJ
AFP28853.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128464
EMBL· GenBank· DDBJ
AFP28854.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128465
EMBL· GenBank· DDBJ
AFP28855.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128468
EMBL· GenBank· DDBJ
AFP28858.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128471
EMBL· GenBank· DDBJ
AFP28861.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128474
EMBL· GenBank· DDBJ
AFP28864.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128475
EMBL· GenBank· DDBJ
AFP28865.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128476
EMBL· GenBank· DDBJ
AFP28866.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128478
EMBL· GenBank· DDBJ
AFP28868.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128480
EMBL· GenBank· DDBJ
AFP28870.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128481
EMBL· GenBank· DDBJ
AFP28871.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128482
EMBL· GenBank· DDBJ
AFP28872.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128484
EMBL· GenBank· DDBJ
AFP28874.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128486
EMBL· GenBank· DDBJ
AFP28876.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128487
EMBL· GenBank· DDBJ
AFP28877.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128492
EMBL· GenBank· DDBJ
AFP28882.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128495
EMBL· GenBank· DDBJ
AFP28885.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128497
EMBL· GenBank· DDBJ
AFP28887.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128500
EMBL· GenBank· DDBJ
AFP28890.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128501
EMBL· GenBank· DDBJ
AFP28891.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128502
EMBL· GenBank· DDBJ
AFP28892.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128505
EMBL· GenBank· DDBJ
AFP28895.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128509
EMBL· GenBank· DDBJ
AFP28899.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128511
EMBL· GenBank· DDBJ
AFP28901.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128513
EMBL· GenBank· DDBJ
AFP28903.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128516
EMBL· GenBank· DDBJ
AFP28906.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128519
EMBL· GenBank· DDBJ
AFP28909.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128522
EMBL· GenBank· DDBJ
AFP28912.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128523
EMBL· GenBank· DDBJ
AFP28913.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128524
EMBL· GenBank· DDBJ
AFP28914.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128526
EMBL· GenBank· DDBJ
AFP28916.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128527
EMBL· GenBank· DDBJ
AFP28917.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128529
EMBL· GenBank· DDBJ
AFP28919.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128530
EMBL· GenBank· DDBJ
AFP28920.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128532
EMBL· GenBank· DDBJ
AFP28922.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128535
EMBL· GenBank· DDBJ
AFP28925.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128537
EMBL· GenBank· DDBJ
AFP28927.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128538
EMBL· GenBank· DDBJ
AFP28928.1
EMBL· GenBank· DDBJ
Genomic DNA
JX128542
EMBL· GenBank· DDBJ
AFP28932.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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