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D3VAX9 · D3VAX9_XENNA

Function

function

CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Features

Showing features for binding site.

130620406080100120140160180200220240260280300
TypeIDPosition(s)Description
Binding site142Mn2+ (UniProtKB | ChEBI)
Binding site209Mn2+ (UniProtKB | ChEBI)
Binding site222Mn2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular FunctionDNA binding
Molecular FunctionDNA endonuclease activity
Molecular Functionmetal ion binding
Biological Processdefense response to virus
Biological Processmaintenance of CRISPR repeat elements

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    CRISPR-associated endonuclease Cas1
  • EC number

Gene names

    • Name
      cas1
    • Ordered locus names
      XNC1_3723

Organism names

Accessions

  • Primary accession
    D3VAX9

Proteomes

Interaction

Subunit

Homodimer, forms a heterotetramer with a Cas2 homodimer.

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for compositional bias, region.

Type
IDPosition(s)Description
Compositional bias277-291Pro residues
Region277-306Disordered

Sequence similarities

Belongs to the CRISPR-associated endonuclease Cas1 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    306
  • Mass (Da)
    33,709
  • Last updated
    2010-04-20 v1
  • MD5 Checksum
    C3BE7DC07D6AF7C0A39A823F0432F7EC
MAYIPLKPIPIKDRNSMIFIGMGRIDVKDNAFVVIDEVNGERMHIPVGSIACIMLEPGTRISHAAVKLASTTGTLLIWVGEAGVRLYSVGQPGGARSDRLLYQAKLALDEDLRLKVVRKMFELRFGEPAPQRRNVEQLRGIEGARVRKSYQILAKQYGVKWQGRNYDHTDWDKGDLINRCISAATSCLYGVTEAAILAAGYAPAIGFLHTGKPLSFVYDIADILKFDTVVPIAFKVAASNSMTPDRQVRIACREKFRTDRTLKRLIPLIEEILAAGEISPPPPPADAQPPAIPEPISIGDIGHRSQ

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias277-291Pro residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FN667742
EMBL· GenBank· DDBJ
CBJ91754.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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