D3VAX9 · D3VAX9_XENNA
- ProteinCRISPR-associated endonuclease Cas1
- Genecas1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids306 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
Cofactor
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 142 | Mn2+ (UniProtKB | ChEBI) | |||
Binding site | 209 | Mn2+ (UniProtKB | ChEBI) | |||
Binding site | 222 | Mn2+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | DNA binding | |
Molecular Function | DNA endonuclease activity | |
Molecular Function | metal ion binding | |
Biological Process | defense response to virus | |
Biological Process | maintenance of CRISPR repeat elements |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCRISPR-associated endonuclease Cas1
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Morganellaceae > Xenorhabdus
Accessions
- Primary accessionD3VAX9
Proteomes
Interaction
Subunit
Homodimer, forms a heterotetramer with a Cas2 homodimer.
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for compositional bias, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 277-291 | Pro residues | |||
Region | 277-306 | Disordered | |||
Sequence similarities
Belongs to the CRISPR-associated endonuclease Cas1 family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length306
- Mass (Da)33,709
- Last updated2010-04-20 v1
- MD5 ChecksumC3BE7DC07D6AF7C0A39A823F0432F7EC
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 277-291 | Pro residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
FN667742 EMBL· GenBank· DDBJ | CBJ91754.1 EMBL· GenBank· DDBJ | Genomic DNA |