D3VAI3 · D3VAI3_XENNA
- ProteinGlucosamine-6-phosphate deaminase
- GenenagB
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids268 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
Catalytic activity
- alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4+
Activity regulation
Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
Pathway
Amino-sugar metabolism; N-acetylneuraminate degradation; D-fructose 6-phosphate from N-acetylneuraminate: step 5/5.
Features
Showing features for active site, site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 72 | Proton acceptor; for enolization step | |||
Active site | 141 | For ring-opening step | |||
Active site | 143 | Proton acceptor; for ring-opening step | |||
Active site | 148 | For ring-opening step | |||
Site | 151 | Part of the allosteric site | |||
Site | 158 | Part of the allosteric site | |||
Site | 160 | Part of the allosteric site | |||
Site | 161 | Part of the allosteric site | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | glucosamine-6-phosphate deaminase activity | |
Molecular Function | identical protein binding | |
Biological Process | carbohydrate metabolic process | |
Biological Process | glucosamine catabolic process | |
Biological Process | N-acetylglucosamine catabolic process | |
Biological Process | N-acetylneuraminate catabolic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlucosamine-6-phosphate deaminase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Morganellaceae > Xenorhabdus
Accessions
- Primary accessionD3VAI3
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 17-230 | Glucosamine/galactosamine-6-phosphate isomerase | |||
Sequence similarities
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length268
- Mass (Da)29,955
- Last updated2010-04-20 v1
- MD5 Checksum64B997C0E8312EB00DF15C64E2956B64
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
FN667742 EMBL· GenBank· DDBJ | CBJ89419.1 EMBL· GenBank· DDBJ | Genomic DNA |