D3UBG7 · D3UBG7_COLLI
- ProteinLactosylceramide 4-alpha-galactosyltransferase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids360 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
Catalytic activity
- a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-alpha-D-galactose = a globoside Gb3Cer (d18:1(4E)) + UDP + H+This reaction proceeds in the forward direction.
- a beta-D-Gal-(1<->1')-ceramide + UDP-alpha-D-galactose = alpha-D-Gal-(1->4)-beta-D-Gal-(1<->1')-Cer + UDP + H+This reaction proceeds in the forward direction.
Pathway
Glycolipid biosynthesis.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | Golgi membrane | |
Molecular Function | galactosyltransferase activity | |
Biological Process | glycosphingolipid biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended nameLactosylceramide 4-alpha-galactosyltransferase
- EC number
- Alternative names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Neoaves > Columbimorphae > Columbiformes > Columbidae > Columba
Accessions
- Primary accessionD3UBG7
Subcellular Location
UniProt Annotation
GO Annotation
Golgi apparatus membrane ; Single-pass type II membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 20-36 | Helical | |||
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 46-61 | Polar residues | |||
Region | 46-73 | Disordered | |||
Domain | 222-347 | Alpha 1,4-glycosyltransferase | |||
Sequence similarities
Belongs to the glycosyltransferase 32 family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length360
- Mass (Da)40,561
- Last updated2010-04-20 v1
- MD5 Checksum14AF1BD6B1B210B063E77D5A9B3D304C
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 46-61 | Polar residues | |||
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
FJ971844 EMBL· GenBank· DDBJ | ADC84388.1 EMBL· GenBank· DDBJ | mRNA |