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D3E2P9 · D3E2P9_METRM

Function

function

Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site.

169150100150200250300350400450500550600650
TypeIDPosition(s)Description
Binding site143Zn2+ (UniProtKB | ChEBI)
Binding site146Zn2+ (UniProtKB | ChEBI)
Binding site155Zn2+ (UniProtKB | ChEBI)
Binding site158Zn2+ (UniProtKB | ChEBI)
Binding site328ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentaminoacyl-tRNA synthetase multienzyme complex
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionmethionine-tRNA ligase activity
Molecular FunctiontRNA binding
Biological Processmethionyl-tRNA aminoacylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Methionine--tRNA ligase
  • EC number
  • Alternative names
    • Methionyl-tRNA synthetase
      (MetRS
      )

Gene names

    • Name
      metG
    • Ordered locus names
      mru_0959

Organism names

Accessions

  • Primary accession
    D3E2P9

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for motif, region, domain.

Type
IDPosition(s)Description
Motif11-21'HIGH' region
Motif325-329'KMSKS' region
Region549-584Disordered
Domain595-691TRNA-binding

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    691
  • Mass (Da)
    78,921
  • Last updated
    2010-03-23 v1
  • MD5 Checksum
    E986C26D3555AB30A90A48D6C365D02F
MTKIFISCALPYANGPCHLGHLRSTYIPADIYARYNRMAGNDVLMVCATDEHGTPIAVKADAEGKKPIEVAKRYHDMIARDIESCDISLDNFARTSDELHYKISQDFFLYLYEKGLIYEEAIQQLYCENCEKFLPDRYVEGICPVCGAEARGDHCESCGRALEPTELLEPHCLTCGNTPVIRDSTQYFFKLSHFQNQLEEYITTNEYLPPNVRNYAQNWLKEGLEDWIMTRDMKWGIPVPLEGAKGKVIYVWGEAFIGYISSAAAWSRRTGIPWEDYWDGHVVHFIGKDIIYHHSLFWPAMLMGHDCKLPDDIFAGEFLSLEGRKMSTSKNWVVWVSDFVKDFESDLLRFYLTISAPLNKDTDFSWDDFGRRVNDELADIIGNFLHRTFTFTHKFFDGKVPEYANPSEEDLEFEAEIKELPAKVGELISSMKFREGLVEILKTAKSANKYFNDQEPWKAVKENPQKASNCLYLSNQFCKSLAILLKPYIPNKADAICDIINISKENVWDDASIFLENGHEINKAKPLFKKIEDKVIEAQKEKLYANLEDSEETKDDKDNKKDKKDKSNKNKSNKDKKDKSKSNDGEKMDLISIDEFAKVEIRIGKIVEIEKIEKSNKLLKTQIDIGDKTIQVIAGLGKRYAPEDLLGKKVPVVTNLKPAKLMGELSEGMIMATESAAILTPDDCEIGELLM

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP001719
EMBL· GenBank· DDBJ
ADC46810.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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