D2TM33 · D2TM33_CITRI
- ProteinPTS system mannose-specific EIIAB component
- GenemanX
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids322 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
function
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport.
Catalytic activity
- D-mannose(out) + N(pros)-phospho-L-histidyl-[protein] = D-mannose 6-phosphate(in) + L-histidyl-[protein]
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 10 | Tele-phosphohistidine intermediate; for EIIA activity | |||
Active site | 174 | Pros-phosphohistidine intermediate; for EIIB activity | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | plasma membrane | |
Molecular Function | kinase activity | |
Molecular Function | protein-N(PI)-phosphohistidine-sugar phosphotransferase activity | |
Biological Process | phosphoenolpyruvate-dependent sugar phosphotransferase system | |
Biological Process | phosphorylation |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePTS system mannose-specific EIIAB component
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Citrobacter
Accessions
- Primary accessionD2TM33
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for modified residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Modified residue | 10 | Phosphohistidine; by HPr | |||
Modified residue | 55 | N6-acetyllysine | |||
Modified residue | 174 | Phosphohistidine; by EIIA | |||
Modified residue | 233 | N6-acetyllysine | |||
Keywords
- PTM
Interaction
Structure
Sequence
- Sequence statusComplete
- Length322
- Mass (Da)34,893
- Last updated2010-03-02 v1
- Checksum31E6382928E40D57
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
FN543502 EMBL· GenBank· DDBJ | CBG88610.1 EMBL· GenBank· DDBJ | Genomic DNA |