D2SYY0 · D2SYY0_ORENI

Function

function

Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses. Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain. In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors. Required for mesendoderm differentiation.

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentapical plasma membrane
Cellular Componentbasolateral plasma membrane
Cellular Componentphotoreceptor inner segment
Molecular Functionglucose transmembrane transporter activity
Biological Processdehydroascorbic acid transport
Biological Processglucose import
Biological Processresponse to insulin

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Solute carrier family 2, facilitated glucose transporter member 1

Gene names

    • Name
      glut1

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Ovalentaria > Cichlomorphae > Cichliformes > Cichlidae > African cichlids > Pseudocrenilabrinae > Oreochromini > Oreochromis

Accessions

  • Primary accession
    D2SYY0

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane7-27Helical
Transmembrane62-84Helical
Transmembrane96-115Helical
Transmembrane121-143Helical
Transmembrane155-178Helical
Transmembrane184-206Helical
Transmembrane271-294Helical
Transmembrane306-327Helical
Transmembrane334-356Helical
Transmembrane362-390Helical
Transmembrane402-425Helical
Transmembrane431-449Helical

Keywords

  • Cellular component

PTM/Processing

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain14-455Major facilitator superfamily (MFS) profile

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    490
  • Mass (Da)
    53,755
  • Last updated
    2010-03-02 v1
  • Checksum
    8C260FD192596762
MDQGKQITLPLLMSVGTAVIGSLQFGYNTGVINAPQKIIENFINQTWSYRYNEPISKTSLTAVWSIAVAIFSVGGIFGSFSVGLFVNRLGRRNSMLMANILAFISAVLMGFSKMAKSWEMLIIGRFVVGLYCGLSTGFVPVYVGEISPTALRGALGTLHQLGIVIGILIAQIFGLEAIMGNDNLWPLLLAFLFIPAVIQCVLLPLCPESPRFLLINKNEENKAKSVLKKLRGTTDVSADMQEMKEESRQMMREKKVTILELFRSPLYRQPLLIAVMLQLSQQLSGINAVFYYSTSIFEKAGVEQPIYATIGAGVVNTAFTVVSLFVVERAGRRSLHLLGLMGMAGSAILMTIALALLDQLRWMSYVSIVAIFAFVAFFEIGPGPIPWFIVAELXSQGPRPSAIAVAGFSNWTANFIVGMGFQYVADACGPYVFVIFTVLLVIFFIFTYFKVPETKGRTFDDITAGFRQTSAMAEKHTPEELNSLGADSQL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FJ914655
EMBL· GenBank· DDBJ
ADB22513.1
EMBL· GenBank· DDBJ
mRNA
FJ914657
EMBL· GenBank· DDBJ
ADB22514.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ914657
EMBL· GenBank· DDBJ
ADB22515.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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