D2NSJ6 · D2NSJ6_ROTMD

Function

function

Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

thiamine diphosphate (UniProtKB | Rhea| CHEBI:58937 )

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site243Mg2+ (UniProtKB | ChEBI)
Binding site273Mg2+ (UniProtKB | ChEBI)
Binding site275Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionmagnesium ion binding
Molecular Functionpyruvate dehydrogenase (acetyl-transferring) activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pyruvate dehydrogenase E1 component
  • EC number

Gene names

    • Ordered locus names
      RMDY18_07900

Organism names

Accessions

  • Primary accession
    D2NSJ6

Proteomes

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain148-314Transketolase N-terminal
Domain493-717Pyruvate dehydrogenase E1 component middle
Domain732-866Transketolase-like C-terminal

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    910
  • Mass (Da)
    101,150
  • Last updated
    2010-03-02 v1
  • MD5 Checksum
    E8319094A455676F116F500D0BBBBC9C
MANVPNEHSLSTLLDGFKDIDVEETQEWAESLEDLIKTHGTERAEYILRALLKEAGAKGVKVPTLVKTDYINTIPVDQQPEYPGDEELERQYRAWIRWNAAIMVQRAQKKGIGVGGHISTFAGIADLYEMGQNHFFRGRNHPGGGDQVFFQGHSSPGVYSRAFVEGVLTEEQMDGFRQEKTKGANGIPSYPHPRCMPEFWQFPTVSMGLGPLNAIHQASFNKYLHNHKIKDTSEQHVWAFLGDGEMDEPESRGALQLAANEHLDNLTFVVNCNLQRLDGPVRGNGKIVQELEAFFRGAGWHVIKVLWGSDYDELLKKDKSGKLIQLMNETLDGDYQTFRGEDGGYIREHFFGKYPETKELVADLTDEQIFNLRLGGHDDKKLYAAYKEAMETKGKPTVILAQSIKGAELGPYFEARNSTHQIKKFTMEALKGFRDHLNIPISDEELEKDLYNPPYYVPEASHPALQYMHARRKELGGYIPGRANTQPEIILPESKVYAQTKKGSGKQTAATTMAFVRLMKDLMRVKGFGHRIAPITPDEARTFGMDSFFPSAKLYNPNGQNYVPVDHQLMLTYTESPEGQIVHVGINEAGATAAFIALGSSYDTHGEPMIPIYIFYSMFGFQRTGDGFWAAADQLCRGFVIGATAGRTTLSGEGLQHNDGHSPILASTNPAFKIYDPAYGYEIAHIVERGIEQMYGTKDEDHNVMYYLTVYNEPIHQPAEPANVDVEGIIKGIHKISESPLTSGPKAQLLASGVAVPWAEKAQQLLAEDWGVSADVWSVTSWTELRRDGIAAEEEALLNPNQPARVPYVTQKLAGAAGPIVATTDFASDVPDQIRQFVPNDFATLGADGFGFADTRPGARRFFHIDAESVVVRTLQMLAKRGEVAADVPAKAFAKYDLLNVNANSELEQH

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP011540
EMBL· GenBank· DDBJ
BAI64622.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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