D1LWV8 · D1LWV8_SACKO
- ProteinAlkaline phosphatase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids538 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score2/5
Function
Catalytic activity
- a phosphate monoester + H2O = an alcohol + phosphate
Cofactor
Protein has several cofactor binding sites:
Note: Binds 1 Mg2+ ion.
Note: Binds 2 Zn2+ ions.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 60 | Mg2+ (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 60 | Zn2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Active site | 111 | Phosphoserine intermediate | ||||
Sequence: S | ||||||
Binding site | 174 | Mg2+ (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Binding site | 176 | Mg2+ (UniProtKB | ChEBI) | ||||
Sequence: T | ||||||
Binding site | 336 | Mg2+ (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 341 | Zn2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 345 | Zn2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Binding site | 382 | Zn2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 383 | Zn2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Binding site | 462 | Zn2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: H |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | side of membrane | |
Molecular Function | alkaline phosphatase activity | |
Molecular Function | metal ion binding |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAlkaline phosphatase
- EC number
Organism names
- Taxonomic lineageEukaryota > Metazoa > Hemichordata > Enteropneusta > Harrimaniidae > Saccoglossus
Accessions
- Primary accessionD1LWV8
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-24 | |||||
Sequence: MVAINMNLVGLLFAFLVFFQVASS | ||||||
Chain | PRO_5003024547 | 25-538 | Alkaline phosphatase | |||
Sequence: EDLAFWKEKAARDIRRAQRLKIKNKVAKKVVLFLGDGNSISTITATRIYKGQLQQGASGEEYELFYERFPNVGLAKTYCADRQVPDSAASGTAYLCGVKTNYNTIGMDDRVEFGNCTQDNPNEYAVDSILKIAQDAGKATGIVTTTRITHATPACTYAHAASRYWEGDDNMPKEERDKGCKDIAWQLVNELPGRNMRVILGGGRQEFLPNFTSDPEDKGKFGQRLDGVNLAETWLASKPDNSKSFFVWNETSFDDVNPESADYLLGLFERSHMNYEANRPNDTAGEPSLADMTEKAIRMLKKYNKGYFLLVEGGRMDHSHHEGIGYHALVDGVAFEEAIKRASDITNDDDTLTIVTADHSFAFDILGYASRGNPILGVNDIDVDQNGQTFTTLHYPDGPGSHYTLEAINHTGLRPIITNPQSRDYLQQALVPNKWASHDGEDVMIYAKGPMAHLFHSTHEQTYIMHAMQYAACIGDDNTNQCKSKNEPMTCGSMNIMTNYGTMMFIVFGLLMQS |
Keywords
- PTM
Structure
Sequence
- Sequence statusComplete
- Length538
- Mass (Da)59,926
- Last updated2010-01-19 v1
- Checksum8C087B0721E5C543
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
GU075935 EMBL· GenBank· DDBJ | ACY92464.1 EMBL· GenBank· DDBJ | mRNA |