D1L2W8 · D1L2W8_BPK32

Function

function

Component of the cylindrical core that assembles on the inner surface of the capsid during capsid formation and plays a role in viral DNA ejection into the host cell. The inner core is composed of stacked rings of gp14, gp15 and gp16 proteins. Following binding to the host cell surface, the internal core is disassembled and gp15 is ejected along with gp14 and gp16 into the infected cell. Gp15 probably remains associated with gp16. The gp15-gp16 complex binds to both the viral DNA and the host inner membrane, probably escorting the leading end of the genome through the periplasm and controlling the extend of DNA translocated into the host cell.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componenthost cell periplasmic space
Cellular Componentvirion component
Biological Processsymbiont genome ejection through host cell envelope, short tail mechanism

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Internal virion protein gp15

Gene names

    • Name
      35

Organism names

Accessions

  • Primary accession
    D1L2W8

Proteomes

Subcellular Location

Virion
Host periplasm
Note: The gp15-gp16 complex spans the periplasm and the cytoplasmic membrane.

Keywords

Interaction

Subunit

Homooctamer. Interacts with gp16; after ejection the gp15-gp16 complex composed of a gp15 octamer and a gp16 tetramer probably binds both the viral DNA and the host inner membrane. Interacts with gp14.

Family & Domains

Features

Showing features for coiled coil, region, compositional bias.

TypeIDPosition(s)Description
Coiled coil688-717
Region725-756Disordered
Compositional bias728-756Basic and acidic residues

Sequence similarities

Belongs to the T7virus internal virion protein gp15 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    756
  • Mass (Da)
    85,637
  • Last updated
    2010-01-19 v1
  • Checksum
    0802CF955FCFEFDF
MASKLEQALNQIPQAGSTRIRGGAASMQYRPVTIQQEGARQSNLVQSLAKFGAAMGEAADAYDKRQRDKAEERSDEIIRKLTPEQRREAIKNGTLLYQDDPYAMEALRFKTGRNAAFLIDDEVAQKVQNGEFRTRTEMEEYRHKRLTEGANEYAEQFMINPEDSEFQRGFNANITERNISLYGKHDTFLSDQAQKGAILASKVELSGVLKDPAVLARPESGEFFQRYIDNALKTGSIPSDAQAQQVIIGSLNDVIQRPGATNFLQSLEDRPVTLNGKTSTYKELMGEEQWNALMVKAQSTQFDNDAKLSEGFRLGITSALNQDDTSKGWEMLQGAKAELDRLQPGEQMTPERERLIQAEEQMQARFRQEAQAAAKEMDKRQKTINKNQVIDQQFTKRINGQYVSTSYKDMPTNENTGEFTHSDMVNYANGKLAEIDQMQLTEQQKDRMKLSYLRADSEGGAFRTVVGQMVTDAGSEWSAAVINGKLPEDTTALNKLRTMRNTDPDLFAALYPDKADLFLTMDMMDKQGIDPQILIDADRSRRSLTKEMQYEDDKAWASLKNNSESPELSRIPASLDGMARKIYDSFKYRTGNSDGAMQQVDKFLKESTVTFKGDDMDGDTIGIIPKNALQVSDDPKSWEQGRDILEEARKGIIAANPWVTNKQLTMYQQGDSIYMMDTTGTVRIRYDKELLTRTYQEQQQRLAKEAEEKALKEATKRAPIAAVNQVRKDIKSGKRKGLAQRSQEFREQRLHRKPKE

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias728-756Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
GQ413937
EMBL· GenBank· DDBJ
ACY66697.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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