D1KBJ2 · D1KBJ2_9GAMM

Function

function

Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

Features

Showing features for dna binding.

160350100150200250300350400450500550600
TypeIDPosition(s)Description
DNA binding564-583H-T-H motif

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular ComponentDNA-directed RNA polymerase complex
Molecular FunctionDNA binding
Molecular Functionsigma factor activity
Biological ProcessDNA-templated transcription initiation

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    RNA polymerase sigma factor RpoD
  • Alternative names
    • Sigma-70

Gene names

    • Name
      rpoD
    • ORF names
      Sup05_0106

Organism names

Accessions

  • Primary accession
    D1KBJ2

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Interacts transiently with the RNA polymerase catalytic core.

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, motif, domain.

Type
IDPosition(s)Description
Region370-440Sigma-70 factor domain-2
Motif394-397Interaction with polymerase core subunit RpoC
Domain394-407RNA polymerase sigma-70
Region449-525Sigma-70 factor domain-3
Region538-591Sigma-70 factor domain-4
Domain563-589RNA polymerase sigma-70

Sequence similarities

Belongs to the sigma-70 factor family. RpoD/SigA subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    603
  • Mass (Da)
    68,935
  • Last updated
    2010-01-19 v1
  • Checksum
    29F7D067294B3E88
MKTTTKAHKQALQKLIMIGKEQGYLTYAEINDILPEDLLTQEQVEPIVTILEELDIAVSDTVPDADTLVVESGAKAQSTSAEAAVAALAALDSEFGRTTDPVRMYMREMGVVDLLEQSDEIRIAKEIEAGVFEIMKSITLYPAITGFFFKAHTRLEEGKCKMTDVIIGYQGDAEDFAKKKAAFDAGEFDDDEEYEEMEEMEYTGPDEGQVYGRFETVLKCSEAYQKTNEKHGFRDKKTIAARQQLSEGLSDLRLAPKLVSTMMEVICDRVALVKKQEKTIQSACLYAGMEREQFFKLFNDNETNFDWLKGAKLDKKVAEALKVSKDEIYYAQKNLLEFEEEMQLTVPELKALNKLYRRGDRRAKKAKSQMIEANLRLVISIAKKYANRGLQFLDLIQEGNVGLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQARTIRIPVHMIETINKLNRVRRQLLQKFGREATPEELAVEMELPEYKINKILKIAKEPLSMETPVGDDEDSNIGDFIEDTNLSSPVEITTRESLKETTGELLANLSPREAKVLKMRFGIDMNTDHTLEEVGRQFDVTRERIRQIEAKALRKLRHPSRAHKLQSFLE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
GG729980
EMBL· GenBank· DDBJ
EEZ80491.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp