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D0Z698 · D0Z698_9TELE

Function

function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Molecular FunctionNADH dehydrogenase activity
Biological ProcessATP synthesis coupled electron transport
Biological Processelectron transport coupled proton transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-ubiquinone oxidoreductase chain 5
  • EC number

Gene names

    • Name
      ND5

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Alepocephali > Alepocephaliformes > Alepocephalidae > Bathytroctes

Accessions

  • Primary accession
    D0Z698

Subcellular Location

Mitochondrion inner membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane6-24Helical
Transmembrane45-64Helical
Transmembrane90-110Helical
Transmembrane122-139Helical
Transmembrane145-165Helical
Transmembrane177-195Helical
Transmembrane215-235Helical
Transmembrane247-267Helical
Transmembrane279-300Helical
Transmembrane331-353Helical
Transmembrane374-393Helical
Transmembrane413-434Helical
Transmembrane463-479Helical
Transmembrane491-511Helical
Transmembrane594-611Helical

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain73-123NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Domain139-422NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Domain428-609NADH dehydrogenase subunit 5 C-terminal

Sequence similarities

Belongs to the complex I subunit 5 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    612
  • Mass (Da)
    67,378
  • Last updated
    2010-01-19 v1
  • MD5 Checksum
    B734264BE32143A7B1BC8FD78B9E5C5B
MQPTALILSTSLMLIFGLLLYPLITTLSPNPRENNWATTHVKTGVSTAFAVSLLPLFIFLDQGVETIVTNWHWMNTATFDINISLKFDHYSIIFTSVALYVTWSILEFALWYMHADPSMNRFFKYLLLFLVAMIILVTANNMFQLFIGWEGVGIMSFLLIGWWYGRADANTAALQAVLYNRVGDIGLIMAMAWFAMNLNSWEIQQMFFTSKEFNLTLPLIGLIVAAAGKSAQFGLHPWLPSAMEGPTPVSALLHSSTMVVAGIFLLIRLHPLMQDNQVALTVCLCLGALTTLFTAICALTQNDIKKIVAFSTSSQLGLMMVTIGLNQPQLAFLHICTHAFFKAMLFLSSGSIIHSLNDEQDIRKMGGLHNLMPLTSSCLTVGSLALTGTPFLAGFFSKDAIIEALNTSYLNAWALALTLIATSFTAVYSFRMVFFVSMGTPRFLALSPINENNPSVINPLKRLAWGSIIAGLIITSNFLPSKTPIMTMPPLLKLAALAVTIIGLLTAMELASLTNKQFKTTPTIPLHNFSNMLGYFPATVHRLIPKLNLTLGQTIATQLVDQTWFEMVGPKGLASAQLKMITNTSNAQRGMIKTYLTIFLLTATLATLLVIL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP009577
EMBL· GenBank· DDBJ
BAI50192.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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