D0V3Y1 · D0V3Y1_TOXGO
- ProteinFormin 2
- GeneFRM2
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids4709 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | actin filament binding | |
Biological Process | cell migration | |
Biological Process | cortical actin cytoskeleton organization | |
Biological Process | regulation of cell shape |
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Taxonomic lineage
Accessions
- Primary accessionD0V3Y1
- Secondary accessions
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-26 | Disordered | ||||
Sequence: MENFRPGPGLAPQARAPPACRRSRRR | ||||||
Region | 72-133 | Disordered | ||||
Sequence: QSAPDSMPSLTPSNHSSPSIDRRAASFCPSPSFFTRSPPAAPAATNGSEGEDDPFCLPSPDT | ||||||
Compositional bias | 73-94 | Polar residues | ||||
Sequence: SAPDSMPSLTPSNHSSPSIDRR | ||||||
Region | 148-303 | Disordered | ||||
Sequence: DIQRVFADPPPRRARSSRSSQRSGSVLSGAGSDGDERSSCSSSPSPLPATACWRGSDASLSDREGQAEAASPRYWRQTVEKAGDMPNAKRVHPVRSRVPDFTTQAALNHGPSGSHSDSAEVCRARPAQWPNSPSAVPPFHPYRAGLPAVDSSPSGA | ||||||
Compositional bias | 161-196 | Polar residues | ||||
Sequence: ARSSRSSQRSGSVLSGAGSDGDERSSCSSSPSPLPA | ||||||
Compositional bias | 248-262 | Polar residues | ||||
Sequence: FTTQAALNHGPSGSH | ||||||
Region | 343-414 | Disordered | ||||
Sequence: PPVSAVGASPATSLTPHSSVSPANADPDRPSNQSPLPKSPPCQPGDVDPVSVHGGLRRTTSCRPTPASVSPY | ||||||
Compositional bias | 347-374 | Polar residues | ||||
Sequence: AVGASPATSLTPHSSVSPANADPDRPSN | ||||||
Region | 433-622 | Disordered | ||||
Sequence: EPGGRSQVEVPTSVSVSSGPSNVESRWSNSLRFNPRTGKIEAPPEDGEASRHRSKGAISPSLTPDGALPSAETSGSLDGSQAFPGRSSGAGPLRKLENGLGPLGGKVTFPPRQSTLYALHAPQPHSPPAVTSPGNSKMRLSSLETGRPHPQWQLPGAPMGGSSSGPKVRPGRTGREDADLHSSTTPLCVS | ||||||
Compositional bias | 440-467 | Polar residues | ||||
Sequence: VEVPTSVSVSSGPSNVESRWSNSLRFNP | ||||||
Compositional bias | 471-485 | Basic and acidic residues | ||||
Sequence: KIEAPPEDGEASRHR | ||||||
Compositional bias | 498-515 | Polar residues | ||||
Sequence: GALPSAETSGSLDGSQAF | ||||||
Compositional bias | 562-580 | Polar residues | ||||
Sequence: VTSPGNSKMRLSSLETGRP | ||||||
Region | 643-670 | Disordered | ||||
Sequence: EEETGRLDGSSGIRSGVASGGPATQGGA | ||||||
Region | 957-986 | Disordered | ||||
Sequence: EASGSLGDTGNRETRAKTEAEGDKGTVTKP | ||||||
Compositional bias | 968-984 | Basic and acidic residues | ||||
Sequence: RETRAKTEAEGDKGTVT | ||||||
Region | 1134-1161 | Disordered | ||||
Sequence: WSSEDSGRAGSRAPAGSNRRTSSSSSSI | ||||||
Compositional bias | 1302-1357 | Polar residues | ||||
Sequence: LGTQSAHRGTSLSGGPTTSSTDALSEGPSCGPSHSRSGSAGSGSVSNPSVAFSNSG | ||||||
Region | 1302-1397 | Disordered | ||||
Sequence: LGTQSAHRGTSLSGGPTTSSTDALSEGPSCGPSHSRSGSAGSGSVSNPSVAFSNSGGVTARALRRRTEAPGGPGAREGSGALAASPRGEGGLHHSF | ||||||
Region | 1528-1559 | Disordered | ||||
Sequence: ASCRAAPGRQGSGSGSIGGLTSRKLGDKGRSG | ||||||
Compositional bias | 1632-1647 | Polar residues | ||||
Sequence: ETSPFPSRTPSPTNCG | ||||||
Region | 1632-1657 | Disordered | ||||
Sequence: ETSPFPSRTPSPTNCGRETPGHKKFG | ||||||
Region | 1702-1822 | Disordered | ||||
Sequence: ATVGTETRQPFDARGVEGSTSQRDSLERKSRGIENSPAESCASPGAPSLSSGGSTTASTSVSVQKEGESSGGTFLSPRLKLPKNLFKKRSGSPGGNDGLAKGQEKGEGRASAQGGSSSCLA | ||||||
Compositional bias | 1742-1772 | Polar residues | ||||
Sequence: CASPGAPSLSSGGSTTASTSVSVQKEGESSG | ||||||
Region | 1894-1960 | Disordered | ||||
Sequence: VEARRSFEPPDQDATRKTASGDGCEGSSTSGSVNASVPHSPTVLSQSRDHLMRRSGSRRTPAAGAEE | ||||||
Compositional bias | 1914-1943 | Polar residues | ||||
Sequence: GDGCEGSSTSGSVNASVPHSPTVLSQSRDH | ||||||
Compositional bias | 1944-1959 | Basic and acidic residues | ||||
Sequence: LMRRSGSRRTPAAGAE | ||||||
Region | 1980-2022 | Disordered | ||||
Sequence: RKSSGPSFQGTRLGTSGPAGSSRGQDEEIRDPQADDSSRLPGL | ||||||
Compositional bias | 1981-2001 | Polar residues | ||||
Sequence: KSSGPSFQGTRLGTSGPAGSS | ||||||
Region | 2089-2131 | Disordered | ||||
Sequence: KHSASPEDADAPPGKEGGKGQQEREKVARRWSGGALKTDQRGS | ||||||
Compositional bias | 2096-2120 | Basic and acidic residues | ||||
Sequence: DADAPPGKEGGKGQQEREKVARRWS | ||||||
Region | 2199-2236 | Disordered | ||||
Sequence: TGPAVRRPSRTLSPSPPVSSLPASLSPGTPGFPAASGV | ||||||
Compositional bias | 2210-2224 | Polar residues | ||||
Sequence: LSPSPPVSSLPASLS | ||||||
Region | 2266-2377 | Disordered | ||||
Sequence: TCDEGRTASPRSSSPSLRAGALSDARSDDGKKGADEQETGDRREKNEPGRTKRLEEESDQRGRYGGGTGLGALASWLGFPGSGTSSRASAGDTSEQRLGRADGDLCGPISPC | ||||||
Compositional bias | 2270-2285 | Polar residues | ||||
Sequence: GRTASPRSSSPSLRAG | ||||||
Compositional bias | 2289-2327 | Basic and acidic residues | ||||
Sequence: DARSDDGKKGADEQETGDRREKNEPGRTKRLEEESDQRG | ||||||
Compositional bias | 2344-2358 | Polar residues | ||||
Sequence: FPGSGTSSRASAGDT | ||||||
Region | 2393-2412 | Disordered | ||||
Sequence: DQQEKHKGQEAEKQRAAQVS | ||||||
Region | 2570-2604 | Disordered | ||||
Sequence: TLMPLGPTAAPSVGSRGPSVSSGQTATPGEPQPTT | ||||||
Compositional bias | 2583-2603 | Polar residues | ||||
Sequence: GSRGPSVSSGQTATPGEPQPT | ||||||
Compositional bias | 2632-2649 | Polar residues | ||||
Sequence: SSEYPQPASGSLPSGTGS | ||||||
Region | 2632-2687 | Disordered | ||||
Sequence: SSEYPQPASGSLPSGTGSCHGRETGERGAGEDTRESAFSGDPVHDPSGDAGAARCF | ||||||
Compositional bias | 2655-2670 | Basic and acidic residues | ||||
Sequence: TGERGAGEDTRESAFS | ||||||
Region | 2749-2824 | Disordered | ||||
Sequence: ACGSSGPNSPTAVMSEGGSLEPDRTLGSFGGWRRQRRMAPVPQRPGQLKPRQTPACSSSTAQPPRGPLAGASLPTH | ||||||
Compositional bias | 2798-2813 | Polar residues | ||||
Sequence: PRQTPACSSSTAQPPR | ||||||
Region | 2941-2970 | Disordered | ||||
Sequence: ASGSEPGFSGAQVVAPGAASQPGGTGGGAV | ||||||
Region | 3032-3065 | Disordered | ||||
Sequence: DVVPAPTGDTGSRAPSHDEGATAGSVGPAGDALT | ||||||
Region | 3081-3100 | Disordered | ||||
Sequence: GGETSARGDNTNASGKLESA | ||||||
Region | 3187-3275 | Disordered | ||||
Sequence: PSVPGSSVPTSGMLVPGATEGDTKEGGETATGAGTQGSTVFLGTPPQVNMLGQGSGGPGGSPPVGSALAGTPGVQGSVGGSSSNVSASG | ||||||
Compositional bias | 3215-3237 | Polar residues | ||||
Sequence: TATGAGTQGSTVFLGTPPQVNML | ||||||
Compositional bias | 3261-3275 | Polar residues | ||||
Sequence: QGSVGGSSSNVSASG | ||||||
Region | 3294-3425 | Disordered | ||||
Sequence: HSVDLGKVPAPQPPTASGDSPSPTGSYPGASDKSQQTFSAGAPSSGTNARTESTPAGAGETGASGEAKAPAAPKKKAMPPPPPPGKTPGDASKAPGGPPGKGKAPPLPKGKKAPQLGKAPKAGGPPKKADAV | ||||||
Compositional bias | 3312-3351 | Polar residues | ||||
Sequence: DSPSPTGSYPGASDKSQQTFSAGAPSSGTNARTESTPAGA | ||||||
Compositional bias | 3367-3382 | Pro residues | ||||
Sequence: KKKAMPPPPPPGKTPG | ||||||
Domain | 3423-3859 | FH2 | ||||
Sequence: DAVDPMTLPLRRKIHWKTLGKEQIEGTVFKELEGDPAIPDMFDPEAISRLFSATLTVKSDEAAVKAAPKKAEEKKHTILDNKRAQNVAIVLARLPLSLDAIAQKMLHLDTEGLTVDILQKVEQVAPTPEELVKFREYEELKKTENTGDLRDVEKKMTALIPVTRLSSRVRVMQTALQWEKVVEEIEKQLALLCKAADEAHNSRKFRSLLQAVLQWGNYVNHGVKKAPKGQEVSSESEARKAETTSPTEGDRRENRQTLQQLPPILLVKELPTKGFKLASLEKLMEFRTTVDKSICSLHFIISNLIVSLPELDILDLASDMPSLEAAARLSDESIDAPVSYLRNEAAFLLSQIHAIKQVLAAKDATATDPSGAPRPSGSKPQTDEALHAELTRLQKLHGEMVLTLERLRESYLNCKAVIGEVGRFYGEDGPKKPSAGK | ||||||
Region | 3648-3677 | Disordered | ||||
Sequence: APKGQEVSSESEARKAETTSPTEGDRRENR | ||||||
Compositional bias | 3650-3677 | Basic and acidic residues | ||||
Sequence: KGQEVSSESEARKAETTSPTEGDRRENR | ||||||
Region | 3952-4145 | Disordered | ||||
Sequence: GCRGSDAEQVAGRPQDADKAGSSVVSSPRTTPRGSIASRGGKKLIVGRHGPEAGGTPQIPRGPPKSDNGSFTETQRLGRGLSEGSEDALSSPRSAERNGSARGRLPSGTNDGAGTGVMRSWSQAGSKTASMGARFKTSSSEAVHAGDGIRSKTRRSSVSPPSKEESSSRRVSVATSHEGDTDKPETLPGPRNWC | ||||||
Compositional bias | 3971-3985 | Polar residues | ||||
Sequence: AGSSVVSSPRTTPRG | ||||||
Compositional bias | 4014-4030 | Polar residues | ||||
Sequence: PPKSDNGSFTETQRLGR | ||||||
Compositional bias | 4064-4088 | Polar residues | ||||
Sequence: AGTGVMRSWSQAGSKTASMGARFKT | ||||||
Compositional bias | 4103-4125 | Polar residues | ||||
Sequence: KTRRSSVSPPSKEESSSRRVSVA | ||||||
Compositional bias | 4204-4221 | Polar residues | ||||
Sequence: ISVTSASGVQSPSGGTSE | ||||||
Region | 4204-4362 | Disordered | ||||
Sequence: ISVTSASGVQSPSGGTSEASLRREAADRLPPGGNRTPPTVRGTIESASNADNPSSLQTMSTPRPVSLGGAQPAERDVQANGENERLRFDSREELRSEDSKSKVGDEDGQATSSPGESNPLAVNSSAVMELHSRSSATPCSSPRAARSGTAAAVGSEPKT | ||||||
Compositional bias | 4242-4268 | Polar residues | ||||
Sequence: TVRGTIESASNADNPSSLQTMSTPRPV | ||||||
Compositional bias | 4281-4308 | Basic and acidic residues | ||||
Sequence: QANGENERLRFDSREELRSEDSKSKVGD | ||||||
Compositional bias | 4309-4347 | Polar residues | ||||
Sequence: EDGQATSSPGESNPLAVNSSAVMELHSRSSATPCSSPRA | ||||||
Region | 4454-4506 | Disordered | ||||
Sequence: VSAPHHFPSSRSRPATPFPVEESEHLANAGSHQGPGALTGTTAKQHPAHKGNS | ||||||
Compositional bias | 4487-4501 | Polar residues | ||||
Sequence: GPGALTGTTAKQHPA | ||||||
Region | 4539-4615 | Disordered | ||||
Sequence: GNELLSEAGDNHPTAAKGEESASKLRPDEDTQRGQSKQASLVNQDAGQHAMSGRQETGAVATESREAASKENGDGTK | ||||||
Compositional bias | 4551-4571 | Basic and acidic residues | ||||
Sequence: PTAAKGEESASKLRPDEDTQR | ||||||
Compositional bias | 4572-4597 | Polar residues | ||||
Sequence: GQSKQASLVNQDAGQHAMSGRQETGA | ||||||
Region | 4660-4709 | Disordered | ||||
Sequence: RRPIICRPRRPPPPVVAKHPVGATGPKAPATATAPHTSPVRPPPATNRGL |
Sequence similarities
Belongs to the formin homology family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length4,709
- Mass (Da)491,678
- Last updated2009-12-15 v1
- Checksum99F9D0B32C5DC3B5
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 73-94 | Polar residues | ||||
Sequence: SAPDSMPSLTPSNHSSPSIDRR | ||||||
Compositional bias | 161-196 | Polar residues | ||||
Sequence: ARSSRSSQRSGSVLSGAGSDGDERSSCSSSPSPLPA | ||||||
Compositional bias | 248-262 | Polar residues | ||||
Sequence: FTTQAALNHGPSGSH | ||||||
Compositional bias | 347-374 | Polar residues | ||||
Sequence: AVGASPATSLTPHSSVSPANADPDRPSN | ||||||
Compositional bias | 440-467 | Polar residues | ||||
Sequence: VEVPTSVSVSSGPSNVESRWSNSLRFNP | ||||||
Compositional bias | 471-485 | Basic and acidic residues | ||||
Sequence: KIEAPPEDGEASRHR | ||||||
Compositional bias | 498-515 | Polar residues | ||||
Sequence: GALPSAETSGSLDGSQAF | ||||||
Compositional bias | 562-580 | Polar residues | ||||
Sequence: VTSPGNSKMRLSSLETGRP | ||||||
Compositional bias | 968-984 | Basic and acidic residues | ||||
Sequence: RETRAKTEAEGDKGTVT | ||||||
Compositional bias | 1302-1357 | Polar residues | ||||
Sequence: LGTQSAHRGTSLSGGPTTSSTDALSEGPSCGPSHSRSGSAGSGSVSNPSVAFSNSG | ||||||
Compositional bias | 1632-1647 | Polar residues | ||||
Sequence: ETSPFPSRTPSPTNCG | ||||||
Compositional bias | 1742-1772 | Polar residues | ||||
Sequence: CASPGAPSLSSGGSTTASTSVSVQKEGESSG | ||||||
Compositional bias | 1914-1943 | Polar residues | ||||
Sequence: GDGCEGSSTSGSVNASVPHSPTVLSQSRDH | ||||||
Compositional bias | 1944-1959 | Basic and acidic residues | ||||
Sequence: LMRRSGSRRTPAAGAE | ||||||
Compositional bias | 1981-2001 | Polar residues | ||||
Sequence: KSSGPSFQGTRLGTSGPAGSS | ||||||
Compositional bias | 2096-2120 | Basic and acidic residues | ||||
Sequence: DADAPPGKEGGKGQQEREKVARRWS | ||||||
Compositional bias | 2210-2224 | Polar residues | ||||
Sequence: LSPSPPVSSLPASLS | ||||||
Compositional bias | 2270-2285 | Polar residues | ||||
Sequence: GRTASPRSSSPSLRAG | ||||||
Compositional bias | 2289-2327 | Basic and acidic residues | ||||
Sequence: DARSDDGKKGADEQETGDRREKNEPGRTKRLEEESDQRG | ||||||
Compositional bias | 2344-2358 | Polar residues | ||||
Sequence: FPGSGTSSRASAGDT | ||||||
Compositional bias | 2583-2603 | Polar residues | ||||
Sequence: GSRGPSVSSGQTATPGEPQPT | ||||||
Compositional bias | 2632-2649 | Polar residues | ||||
Sequence: SSEYPQPASGSLPSGTGS | ||||||
Compositional bias | 2655-2670 | Basic and acidic residues | ||||
Sequence: TGERGAGEDTRESAFS | ||||||
Compositional bias | 2798-2813 | Polar residues | ||||
Sequence: PRQTPACSSSTAQPPR | ||||||
Compositional bias | 3215-3237 | Polar residues | ||||
Sequence: TATGAGTQGSTVFLGTPPQVNML | ||||||
Compositional bias | 3261-3275 | Polar residues | ||||
Sequence: QGSVGGSSSNVSASG | ||||||
Compositional bias | 3312-3351 | Polar residues | ||||
Sequence: DSPSPTGSYPGASDKSQQTFSAGAPSSGTNARTESTPAGA | ||||||
Compositional bias | 3367-3382 | Pro residues | ||||
Sequence: KKKAMPPPPPPGKTPG | ||||||
Compositional bias | 3650-3677 | Basic and acidic residues | ||||
Sequence: KGQEVSSESEARKAETTSPTEGDRRENR | ||||||
Compositional bias | 3971-3985 | Polar residues | ||||
Sequence: AGSSVVSSPRTTPRG | ||||||
Compositional bias | 4014-4030 | Polar residues | ||||
Sequence: PPKSDNGSFTETQRLGR | ||||||
Compositional bias | 4064-4088 | Polar residues | ||||
Sequence: AGTGVMRSWSQAGSKTASMGARFKT | ||||||
Compositional bias | 4103-4125 | Polar residues | ||||
Sequence: KTRRSSVSPPSKEESSSRRVSVA | ||||||
Compositional bias | 4204-4221 | Polar residues | ||||
Sequence: ISVTSASGVQSPSGGTSE | ||||||
Compositional bias | 4242-4268 | Polar residues | ||||
Sequence: TVRGTIESASNADNPSSLQTMSTPRPV | ||||||
Compositional bias | 4281-4308 | Basic and acidic residues | ||||
Sequence: QANGENERLRFDSREELRSEDSKSKVGD | ||||||
Compositional bias | 4309-4347 | Polar residues | ||||
Sequence: EDGQATSSPGESNPLAVNSSAVMELHSRSSATPCSSPRA | ||||||
Compositional bias | 4487-4501 | Polar residues | ||||
Sequence: GPGALTGTTAKQHPA | ||||||
Compositional bias | 4551-4571 | Basic and acidic residues | ||||
Sequence: PTAAKGEESASKLRPDEDTQR | ||||||
Compositional bias | 4572-4597 | Polar residues | ||||
Sequence: GQSKQASLVNQDAGQHAMSGRQETGA |