D0IQI5 · D0IQI5_DROME
- Proteinhistone acetyltransferase
- Geneenok-RA
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1092 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score2/5
Function
Catalytic activity
- acetyl-CoA + L-lysyl-[protein] = CoA + H+ + N6-acetyl-L-lysyl-[protein]
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 883 | Proton donor/acceptor | ||||
Sequence: E |
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | nucleosome | |
Molecular Function | DNA binding | |
Molecular Function | histone acetyltransferase activity | |
Molecular Function | metal ion binding | |
Biological Process | nucleosome assembly | |
Biological Process | regulation of DNA-templated transcription |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namehistone acetyltransferase
- EC number
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora
Accessions
- Primary accessionD0IQI5
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 6-82 | SAMD1-like winged helix (WH) | ||||
Sequence: AHDINMDTWNQWILEAISKIRSQKQRPSVQRICQAIGTHHKFHEDIVAEKLEKAVESGAVIKVYNKGLHSYKAPMAK | ||||||
Domain | 89-161 | H15 | ||||
Sequence: KNTNLYKLVAKAVHDLGECEGSTIKSIENYIQKFNCIDLSPNVDFKAVIKASIKKAVDAGFLIQEGKLYKKGK | ||||||
Region | 315-509 | Disordered | ||||
Sequence: ERMTPSYKYASNKRQSIKKDGNIESPSTSKLCVYNDGNGQRRKVPASLSSRKMNHSEDQFEFPSKQKRSQILQGGYLASQETRKRTFSDLSSTSSSSESEDEDDEDDDRNRNGDDNDQDESTSSDSCTSSSSDSDSSESSSDTSEWDDEYDEEEDYDTDRSTIREKNVFESGKQSCAKLSTGDGLGSPQNNELGS | ||||||
Compositional bias | 335-349 | Polar residues | ||||
Sequence: GNIESPSTSKLCVYN | ||||||
Compositional bias | 379-409 | Polar residues | ||||
Sequence: KQKRSQILQGGYLASQETRKRTFSDLSSTSS | ||||||
Compositional bias | 410-427 | Acidic residues | ||||
Sequence: SSESEDEDDEDDDRNRNG | ||||||
Compositional bias | 436-453 | Polar residues | ||||
Sequence: TSSDSCTSSSSDSDSSES | ||||||
Compositional bias | 454-470 | Acidic residues | ||||
Sequence: SSDTSEWDDEYDEEEDY | ||||||
Compositional bias | 487-509 | Polar residues | ||||
Sequence: KQSCAKLSTGDGLGSPQNNELGS | ||||||
Compositional bias | 548-585 | Polar residues | ||||
Sequence: ATSPAANRVQKSTPVASSTPEKNSAPIGGMTIKRQTAN | ||||||
Region | 548-587 | Disordered | ||||
Sequence: ATSPAANRVQKSTPVASSTPEKNSAPIGGMTIKRQTANGQ | ||||||
Compositional bias | 631-656 | Basic and acidic residues | ||||
Sequence: RSRETHSQADGKREMNNDEDAPGEST | ||||||
Region | 631-671 | Disordered | ||||
Sequence: RSRETHSQADGKREMNNDEDAPGESTKRANPFENQPLPPGV | ||||||
Domain | 707-988 | MYST-type HAT | ||||
Sequence: QNTQSPKSIQIGKWDIETWYSSPFPQEYARLLKLFLCEFCLKYTKSRSVLDRHQNKCIWKQPPGTEIFRQGNISVFEVDGNVNKIYCQNLCLLAKFFLDHKTLYYDVEPFLFYILTKNDQSGCHLVGYFSKEKHCTQKYNVSCILTMPQYQRQGYGRFLIDFSYLLSREEGQLGTPEKPLSDLGRLSYFSYWKSVVLEYLYKHRNYTKITFKDIAIKTGLAISDIALAFELLNFIKLRKNDGDIRYQINVKIEWKKVLAHHNKMANSKTRIIIEPDCLRWSP | ||||||
Compositional bias | 1032-1052 | Polar residues | ||||
Sequence: VSTSSKVNQESSELSTKNRGP | ||||||
Region | 1032-1092 | Disordered | ||||
Sequence: VSTSSKVNQESSELSTKNRGPSSEKLIDERENQRKRAYPEEFLKSASNEAKKPKLTAPQPN | ||||||
Compositional bias | 1053-1079 | Basic and acidic residues | ||||
Sequence: SSEKLIDERENQRKRAYPEEFLKSASN |
Sequence similarities
Belongs to the MYST (SAS/MOZ) family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusFragment
- Length1,092
- Mass (Da)123,446
- Last updated2009-12-15 v1
- Checksum9EE6E0A322E3D554
Features
Showing features for compositional bias, non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 335-349 | Polar residues | ||||
Sequence: GNIESPSTSKLCVYN | ||||||
Compositional bias | 379-409 | Polar residues | ||||
Sequence: KQKRSQILQGGYLASQETRKRTFSDLSSTSS | ||||||
Compositional bias | 410-427 | Acidic residues | ||||
Sequence: SSESEDEDDEDDDRNRNG | ||||||
Compositional bias | 436-453 | Polar residues | ||||
Sequence: TSSDSCTSSSSDSDSSES | ||||||
Compositional bias | 454-470 | Acidic residues | ||||
Sequence: SSDTSEWDDEYDEEEDY | ||||||
Compositional bias | 487-509 | Polar residues | ||||
Sequence: KQSCAKLSTGDGLGSPQNNELGS | ||||||
Compositional bias | 548-585 | Polar residues | ||||
Sequence: ATSPAANRVQKSTPVASSTPEKNSAPIGGMTIKRQTAN | ||||||
Compositional bias | 631-656 | Basic and acidic residues | ||||
Sequence: RSRETHSQADGKREMNNDEDAPGEST | ||||||
Compositional bias | 1032-1052 | Polar residues | ||||
Sequence: VSTSSKVNQESSELSTKNRGP | ||||||
Compositional bias | 1053-1079 | Basic and acidic residues | ||||
Sequence: SSEKLIDERENQRKRAYPEEFLKSASN | ||||||
Non-terminal residue | 1092 | |||||
Sequence: N |
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BT100223 EMBL· GenBank· DDBJ | ACY46098.1 EMBL· GenBank· DDBJ | mRNA |