C9ZUL6 · C9ZUL6_TRYB9
- ProteinPhosphoacetylglucosamine mutase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids602 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate
Cofactor
Note: Binds 1 Mg2+ ion per subunit.
Pathway
Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route I): step 2/2.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 82 | Phosphoserine intermediate | ||||
Sequence: S | ||||||
Binding site | 82 | Mg2+ (UniProtKB | ChEBI); via phosphate group | ||||
Sequence: S | ||||||
Binding site | 338 | Mg2+ (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 340 | Mg2+ (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 342 | Mg2+ (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 436-438 | substrate | ||||
Sequence: ESN | ||||||
Binding site | 564-568 | substrate | ||||
Sequence: RPSGT | ||||||
Binding site | 573 | substrate | ||||
Sequence: R |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | metal ion binding | |
Molecular Function | phosphoacetylglucosamine mutase activity | |
Biological Process | carbohydrate metabolic process | |
Biological Process | UDP-N-acetylglucosamine biosynthetic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhosphoacetylglucosamine mutase
- EC number
- Short namesPAGM
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Discoba > Euglenozoa > Kinetoplastea > Metakinetoplastina > Trypanosomatida > Trypanosomatidae > Trypanosoma
Accessions
- Primary accessionC9ZUL6
Proteomes
Organism-specific databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 72-114 | Alpha-D-phosphohexomutase alpha/beta/alpha | ||||
Sequence: GCSVGCMVTASHNPCGDNGLKLIDVDGGMLETSWETTCTQAAN | ||||||
Domain | 246-345 | Phosphoacetylglucosamine mutase AMG1 | ||||
Sequence: QKIVIDAASGVGAVALKSLLKCAQEVTSGVFEEFFDVTVLHDNVDDINALNYMCGADYTQKAQYPSNGTKEWAATYEKRRSDKNEEVHYYSLDGDADRVV | ||||||
Domain | 362-493 | Phosphoacetylglucosamine mutase AMG1 | ||||
Sequence: DGDRISILYALSVREWIGGEALKLLDVGVVQTAYANGASTDYIQRGLGLRTYSSQTGVKNLHPIAHKCDIGAYFESNGHGTILLNGDAIDAKVPSLPSKTRHVLSLLPRLISQVCGDAIANVFACELILLAH | ||||||
Domain | 539-593 | Alpha-D-phosphohexomutase C-terminal | ||||
Sequence: EAIDAAVAAANEATPSSATVARAFARPSGTEPIVRVYAEAATHAVSSKLANDVEE |
Sequence similarities
Belongs to the phosphohexose mutase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length602
- Mass (Da)64,951
- Last updated2009-11-24 v1
- ChecksumC96C5E94A26FB68C
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
FN554971 EMBL· GenBank· DDBJ | CBH13104.1 EMBL· GenBank· DDBJ | Genomic DNA |