C9ZQF7 · C9ZQF7_TRYB9
- ProteinAlkylglycerone-phosphate synthase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids613 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids.
Catalytic activity
- a 1-acylglycerone 3-phosphate + a long chain fatty alcohol = 1-O-alkylglycerone 3-phosphate + a long-chain fatty acid + H+
Cofactor
Pathway
Glycerolipid metabolism; ether lipid biosynthesis.
Features
Showing features for binding site, site, active site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | peroxisome | |
Molecular Function | alkylglycerone-phosphate synthase activity | |
Molecular Function | FAD binding | |
Biological Process | lipid biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAlkylglycerone-phosphate synthase
- EC number
- Short namesAlkyl-DHAP synthase
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Discoba > Euglenozoa > Kinetoplastea > Metakinetoplastina > Trypanosomatida > Trypanosomatidae > Trypanosoma
Accessions
- Primary accessionC9ZQF7
Proteomes
Organism-specific databases
Subcellular Location
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for domain, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 126-307 | FAD-binding PCMH-type | ||||
Sequence: IDRPPDAVILPNNHDDCVKIMELAQKHNVVVVPFGGGTNVTGGVEPNPFETRRMVISIDMRRMGRMLHIDTESGTAVFEVGVLGPDIDEQLSRYGFMMGHDPDSYAYSTLGGWIAARGSGAMSNKYGDIENMILSMRVVTPVGVVETPLTSRPCGVDLNAMFVGSEGAFGLVTEAVVKIERL | ||||||
Region | 573-593 | Disordered | ||||
Sequence: PGKLLPSPPSEKETPKATQAR |
Sequence similarities
Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length613
- Mass (Da)69,084
- Last updated2009-11-24 v1
- Checksum9B75F3984CC968CF
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
FN554969 EMBL· GenBank· DDBJ | CBH11637.1 EMBL· GenBank· DDBJ | Genomic DNA |