C9RNE9 · C9RNE9_FIBSS

Function

function

In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity.

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular Function3'-5' exonuclease activity
Molecular Function5'-3' exonuclease activity
Molecular FunctionDNA binding
Molecular FunctionDNA-directed DNA polymerase activity
Biological ProcessDNA-templated DNA replication
Biological Processdouble-strand break repair

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    DNA polymerase I
  • EC number

Gene names

    • Name
      polA
    • Ordered locus names
      FSU_1227

Organism names

Accessions

  • Primary accession
    C9RNE9

Proteomes

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region, compositional bias.

Type
IDPosition(s)Description
Domain3-2665'-3' exonuclease
Region297-328Disordered
Compositional bias309-328Polar residues
Domain342-5643'-5' exonuclease
Domain729-936DNA-directed DNA polymerase family A palm

Sequence similarities

Belongs to the DNA polymerase type-A family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    972
  • Mass (Da)
    108,239
  • Last updated
    2009-11-24 v1
  • Checksum
    647675732F41235F
MAEKTLLLLDSFALAFRMFYAYSQNPLVNSKGEDVSMMHGYWGAVLRILAKHKPTHFAIARDVAHTKTFRHELYPDYKANRGPMPEEMAAQMPLLCESMEASGIPLLSEPGYEADDVMASAAEAAVNAGFDHVVIISKDKDMSQIVTDKIHLFHLEKGADGIDFGPQQVLEKYGIPPEKIRDYLALMGDSSDNVPGVPKVGPKTAIQLLTEYGDMDNIYANLDNIKKKGLHDNLANNKEQAFLSRELVTLQTKRAYHGNLDALEFCGLHSDTLEGIFREHEINSLIRLLENVPSKTGFVRKDDSDDSAAGSESNGTSDDASGDSSNSKVVKASFPADLPPTYICVDNDEVFEQMKKEFDEATEIGIDTETDGLDPMQCNIVGLCLAAAAKDGSVPKGYYIPLGHTDDIGFPYPAGKGGNFDFNATKKWFIDFWNDSCTLPGDISDSGSKQPDSAKRSLVFHNAKFDLHVLARTFGLTQKQIDSANIIDTLIAAWMLSPGQTGLGLDNQVMQLLQHEMIPIENLIGRGKKQITFNRTPIKDATEYGAEDAVYTLRLWAPLRAKLQKYDYEKYFFSQEMPLLKVLYQMEGVGAFVDTKILKKLQTDLEHRIEKLEKEICDMAGCEFNIGSPKQLGEVLFDTLGLPEIKKRSTDAAVLEELSFRSAHPIVFAVIEYRELKKMQSTYVSVLPTLVNPDTKRIHTSFIQWGTATGRLSSRDPNLQNIPVRSDLGKQIRAAFVPQNPNNVILAVDYSQIELRMLAHLSGDEALIESYKEGIDIHARTAAAINRVSLEDVTADMRRDAKVVNFGVLYGMTAFRLSRDLKIPMAQAKSFIDGYFEMYQGVQKFIDDTKAAAHRDGYVETLSGRRRYIAGIDSSDRMESQMAERMAVNTPVQGSAADLIKIAMIRIQKRINDENLPLRMMLQVHDELVFECPKDQVEALSAMVKSEMEGAMELKVPLVASVGFGKNWLEAH

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias309-328Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP002158
EMBL· GenBank· DDBJ
ADL27094.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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