C9JWC4 · C9JWC4_HUMAN

  • Protein
    Holliday junction recognition protein
  • Gene
    HJURP
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    2/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Cellular Componentnucleolus
Cellular Componentnucleoplasm
Molecular FunctionDNA binding
Molecular Functionhistone binding

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Holliday junction recognition protein

Gene names

    • Name
      HJURP

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    C9JWC4

Proteomes

Organism-specific databases

Subcellular Location

Keywords

  • Cellular component

Disease & Variants

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 577 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

Genetic variation databases

PTM/Processing

Features

Showing features for modified residue (large scale data).

TypeIDPosition(s)SourceDescription
Modified residue (large scale data)93PRIDEPhosphothreonine
Modified residue (large scale data)97PRIDEPhosphoserine
Modified residue (large scale data)100PRIDEPhosphoserine
Modified residue (large scale data)116PRIDEPhosphoserine
Modified residue (large scale data)125PRIDEPhosphoserine
Modified residue (large scale data)126PRIDEPhosphoserine
Modified residue (large scale data)243PRIDEPhosphoserine
Modified residue (large scale data)262PRIDEPhosphoserine
Modified residue (large scale data)327PRIDEPhosphoserine
Modified residue (large scale data)363PRIDEPhosphoserine
Modified residue (large scale data)388PRIDEPhosphoserine
Modified residue (large scale data)401PRIDEPhosphoserine
Modified residue (large scale data)411PRIDEPhosphoserine
Modified residue (large scale data)447PRIDEPhosphoserine
Modified residue (large scale data)472PRIDEPhosphoserine
Modified residue (large scale data)474PRIDEPhosphoserine
Modified residue (large scale data)510PRIDEPhosphoserine
Modified residue (large scale data)556PRIDEPhosphoserine
Modified residue (large scale data)557PRIDEPhosphoserine

Proteomic databases

Expression

Gene expression databases

Structure

Family & Domains

Features

Showing features for region, domain, compositional bias.

TypeIDPosition(s)Description
Region106-141Disordered
Domain186-300Holliday junction recognition protein HJURP central
Domain324-385Holliday junction regulator protein family C-terminal
Region427-489Disordered
Compositional bias430-477Polar residues
Domain469-528Holliday junction regulator protein family C-terminal

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    570
  • Mass (Da)
    64,278
  • Last updated
    2009-11-03 v1
  • Checksum
    600FD3802A8472F1
MLGTLRAMEGEDVEDDQLLQKLRASRRRFQRRMQRLIEKYNQPFEDTPVVQMATLTYETPQGLRIWGGRLIKERNEGEIQCAGNRAGRDVRVTPLPSLASPAVPAPGYCSRISRKSPGDPAKPASSPREWDPLHPSSTDMALVPRNDSLSLQETSSSSFLSSQPFEDDDICNVTISDLYAGMLHSMSRLLSTKPSSIISTKTFIMQNWNSRRRHRYKSRMNKTYCKGARRSQRSSKENFIPCSEPVKGTGALRDCKNVLDVSCRKTGLKLEKAFLEVNRPQIHKLDPSWKERKVTPSKYSSLIYFDSSATYNLDEENRFRTLKWLISPVKIVSRPTIRQGHGENRQREIEIRFDQLHREYCLSPRNQPRRMCLPDSWAMNMYRGGPASPGGLQGLETRRLSLPSSKAKAKSLSEAFENLGKRSLEAGRCLPKSDSSSSLPKTNPTHSATRPQQTSDLHVQGNSSGIFRKSVSPSKTLSVPDKEVPGHGRNRYDEIKEEFDKLHQKYCLKSPGQMTVPLCIGVSTDKASMEVRYQTEGFLGKLNPDPHFQGFQKLPSSPLGCRKSLLGSTA

Computationally mapped potential isoform sequences

There are 4 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q8NCD3HJURP_HUMANHJURP748
F8WCV1F8WCV1_HUMANHJURP122
H7C3V8H7C3V8_HUMANHJURP268
H7C0I6H7C0I6_HUMANHJURP68

Features

Showing features for compositional bias, non-terminal residue.

TypeIDPosition(s)Description
Compositional bias430-477Polar residues
Non-terminal residue570

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC005538
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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