C9JR33 · C9JR33_HUMAN
- ProteinNAD-dependent protein deacetylase sirtuin-2
- GeneSIRT2
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
Catalytic activity
- H2O + N6-hexadecanoyl-L-lysyl-[protein] + NAD+ = 2''-O-hexadecanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamideThis reaction proceeds in the forward direction.
- H2O + N6-tetradecanoyl-L-lysyl-[protein] + NAD+ = 2''-O-tetradecanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamideThis reaction proceeds in the forward direction.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | centriole | |
Cellular Component | microtubule | |
Cellular Component | midbody | |
Cellular Component | myelin sheath | |
Cellular Component | spindle | |
Molecular Function | NAD+ binding | |
Molecular Function | transferase activity |
Keywords
- Molecular function
- Ligand
Names & Taxonomy
Protein names
- Recommended nameNAD-dependent protein deacetylase sirtuin-2
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionC9JR33
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
Disease & Variants
Variants
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The viewer provides 160 variants from UniProt as well as other sources including ClinVar and dbSNP.
Genetic variation databases
PTM/Processing
Features
Showing features for modified residue (large scale data).
Type | ID | Position(s) | Source | Description | |||
---|---|---|---|---|---|---|---|
Modified residue (large scale data) | 16 | PRIDE | Phosphoserine | ||||
Sequence: S |
Proteomic databases
Expression
Gene expression databases
Structure
Sequence
- Sequence statusFragment
- Length73
- Mass (Da)8,218
- Last updated2009-11-03 v1
- Checksum1DCD2F79C4DE481D
Computationally mapped potential isoform sequences
There are 11 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q8IXJ6 | SIR2_HUMAN | SIRT2 | 389 | ||
C9J3U7 | C9J3U7_HUMAN | SIRT2 | 78 | ||
E7EWX6 | E7EWX6_HUMAN | SIRT2 | 237 | ||
F8WF57 | F8WF57_HUMAN | SIRT2 | 39 | ||
F8WCF4 | F8WCF4_HUMAN | SIRT2 | 111 | ||
F8WDM4 | F8WDM4_HUMAN | SIRT2 | 52 | ||
F8WBT6 | F8WBT6_HUMAN | SIRT2 | 96 | ||
C9JZQ0 | C9JZQ0_HUMAN | SIRT2 | 130 | ||
B5MCS1 | B5MCS1_HUMAN | SIRT2 | 169 | ||
A0A0A0MRF5 | A0A0A0MRF5_HUMAN | SIRT2 | 234 | ||
A0AAG2T947 | A0AAG2T947_HUMAN | SIRT2 | 389 |
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 73 | |||||
Sequence: Y |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC011455 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |