C8Z830 · GMT1_YEAS8

Function

function

Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen. Defective copy causes severe glycosylation defect and abnormal retention of soluble endoplasmic reticulum proteins. Involved in vanadate sensitivity (By similarity).

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasmic vesicle membrane
Cellular Componentendoplasmic reticulum membrane
Cellular ComponentGolgi membrane
Biological Processtransmembrane transport

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    GDP-mannose transporter 1
  • Short names
    GMT 1
  • Alternative names
    • Low dye-binding protein 3
    • Morphogenesis checkpoint-dependent protein 3
    • Vanadate resistance glycosylation protein 4

Gene names

    • Name
      VRG4
    • Synonyms
      GOG5, LDB3, MCD3, VAN2, VIG4
    • ORF names
      EC1118_1G1_0463g

Organism names

Accessions

  • Primary accession
    C8Z830

Proteomes

    • Identifier
    • Component
      Chromosome VII, Scaffold EC1118_1G1

Subcellular Location

Golgi apparatus membrane
; Multi-pass membrane protein
Cytoplasmic vesicle membrane
; Multi-pass membrane protein
Endoplasmic reticulum membrane
; Multi-pass membrane protein
Note: Recycles between the Golgi apparatus and the endoplasmic reticulum.

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain1-16Cytoplasmic
Transmembrane17-37Helical
Topological domain38-51Lumenal
Transmembrane52-72Helical
Topological domain73-92Cytoplasmic
Transmembrane93-113Helical
Topological domain114-119Lumenal
Transmembrane120-140Helical
Topological domain141-144Cytoplasmic
Transmembrane145-165Helical
Topological domain166-180Lumenal
Transmembrane181-201Helical
Topological domain202-215Cytoplasmic
Transmembrane216-236Helical
Topological domain237-252Lumenal
Transmembrane253-273Helical
Topological domain274-279Cytoplasmic
Transmembrane280-300Helical
Topological domain301-304Lumenal
Transmembrane305-325Helical
Topological domain326-337Cytoplasmic

Keywords

PTM/Processing

Features

Showing features for chain, glycosylation.

TypeIDPosition(s)Description
ChainPRO_00003916741-337GDP-mannose transporter 1
Glycosylation119N-linked (GlcNAc...) asparagine
Glycosylation242N-linked (GlcNAc...) asparagine
Glycosylation246N-linked (GlcNAc...) asparagine
Glycosylation249N-linked (GlcNAc...) asparagine

Keywords

Proteomic databases

PTM databases

Interaction

Subunit

Homooligomer.

Structure

Family & Domains

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    337
  • Mass (Da)
    37,019
  • Last updated
    2009-11-03 v1
  • Checksum
    5C7EE07B05DA8E61
MSELKTGHAGHNPWASVANSGPISILSYCGSSILMTVTNKFVVNLKDFNMNFVMLFVQSLVCTITLIILRILGYAKFRSLNKTDAKNWFPISFLLVLMIYTSSKALQYLAVPIYTIFKNLTIILIAYGEVLFFGGSVTSMELSSFLLMVLSSVVATWGDQQAVAAKAASLAEGAAGAVASFNPGYFWMFTNCITSALFVLIMRKRIKLTNFKDFDTMFYNNVLALPILLLFSFCVEDWSSVNLTNNFSNDSLTAMIISGVASVGISYCSGWCVRVTSSTTYSMVGALNKLPIALSGLIFFDAPRNFLSILSIFIGFLSGIIYAVAKQKKQQAQPLRK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FN393070
EMBL· GenBank· DDBJ
CAY79546.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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