C8XBB4 · FGD_NAKMY
- ProteinF420-dependent glucose-6-phosphate dehydrogenase
- Genefgd
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids339 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone.
Catalytic activity
- D-glucose 6-phosphate + H+ + oxidized coenzyme F420-(gamma-L-Glu)(n) = 6-phospho-D-glucono-1,5-lactone + reduced coenzyme F420-(gamma-L-Glu)(n)
CHEBI:61548 + CHEBI:15378 + oxidized coenzyme F420-(γ-L-Glu)(n) RHEA-COMP:12939 = CHEBI:57955 + reduced coenzyme F420-(γ-L-Glu)(n) RHEA-COMP:14378
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 41 | coenzyme F420-(gamma-Glu)n (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Active site | 42 | Proton donor | ||||
Sequence: H | ||||||
Binding site | 78 | coenzyme F420-(gamma-Glu)n (UniProtKB | ChEBI) | ||||
Sequence: T | ||||||
Binding site | 109-110 | coenzyme F420-(gamma-Glu)n (UniProtKB | ChEBI) | ||||
Sequence: TG | ||||||
Active site | 111 | Proton acceptor | ||||
Sequence: E | ||||||
Binding site | 114 | coenzyme F420-(gamma-Glu)n (UniProtKB | ChEBI) | ||||
Sequence: N | ||||||
Binding site | 177-178 | coenzyme F420-(gamma-Glu)n (UniProtKB | ChEBI) | ||||
Sequence: SG | ||||||
Binding site | 180-181 | coenzyme F420-(gamma-Glu)n (UniProtKB | ChEBI) | ||||
Sequence: AA | ||||||
Binding site | 195 | substrate | ||||
Sequence: T | ||||||
Binding site | 198 | substrate | ||||
Sequence: K | ||||||
Binding site | 259 | substrate | ||||
Sequence: K | ||||||
Binding site | 283 | substrate | ||||
Sequence: R |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | coenzyme F420 binding | |
Molecular Function | glucose-6-phosphate dehydrogenase (coenzyme F420) activity | |
Molecular Function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | |
Biological Process | carbohydrate metabolic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameF420-dependent glucose-6-phosphate dehydrogenase
- EC number
- Short namesFGD ; G6PD
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Nakamurellales > Nakamurellaceae > Nakamurella
Accessions
- Primary accessionC8XBB4
Proteomes
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000413597 | 1-339 | F420-dependent glucose-6-phosphate dehydrogenase | |||
Sequence: MTPPPIRFGYKASAEQFGPSELADLAVAAEEHGFDSVFISDHLQPWRHDGGHAPASLPWLGAVGARTQRVILGTSVLTPTIRYHPGVIAQAFATLGSMYPGRIVLGVGTGESLNEVPLGLAWPEQKERFARLKESVNLIHELWTGERVTFEGEYYRTDKATIYDRPADPVPIYIGASGPAATRLAGRIADGFITTSGKAPSLYTDTLLPALRDGVEKAGRRLDELDTLMEMKVSFDTDRERAMQDTRFWAALALKPEQKAGVEDPLEMQRLADELPIEQAASRWIVSDDPDEHVEKIRTYLDLGFRHLVFHAPGHDQQRFLALYGEQILPRLRALVGQG |
Interaction
Structure
Sequence
- Sequence statusComplete
- Length339
- Mass (Da)37,533
- Last updated2009-11-03 v1
- ChecksumDF31FCC674D02AF3
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP001737 EMBL· GenBank· DDBJ | ACV77376.1 EMBL· GenBank· DDBJ | Genomic DNA |