C8V4J5 · DBAA_EMENI

Function

function

Transcription factor that regulates the expression of the gene cluster that mediates the biosynthesis of the antibiotic 2,4- dihydroxy-3-methyl-6-(2-oxopropyl)benzaldehyde (DHMBA) and its derivatives (PubMed:23001671).
Probably binds the conserved motif 5'-CT/CCG/AGA/CG/CT/A/CA/TT/A/GC-3' found in all dba cluster promoters and that shows significant similarities to the binding sites of other fungal C6 finger domain transcription factors (Probable)

Features

Showing features for dna binding.

158450100150200250300350400450500550
TypeIDPosition(s)Description
DNA binding24-51Zn2-C6 fungal-type

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleus
Molecular FunctionDNA binding
Molecular FunctionDNA-binding transcription factor activity, RNA polymerase II-specific
Molecular Functionzinc ion binding
Biological ProcessDNA-templated transcription

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    C6 finger domain transcription factor dbaA
  • Alternative names
    • Derivative of benzaldehyde biosynthesis cluster protein A

Gene names

    • Name
      dbaA
    • ORF names
      ANIA_07896

Organism names

Accessions

  • Primary accession
    C8V4J5
  • Secondary accessions
    • Q5AUY4

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004463411-584C6 finger domain transcription factor dbaA

Expression

Induction

Deletion of the conserved eukaryotic csnE deneddylase subunit of the COP9 signalosome leading to defect in protein degradation results in the activation of the silenced dba gene cluster (PubMed:23001671).
Expression is controlled by the transcription factor flbB (PubMed:25701285).

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region1-24Disordered

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    584
  • Mass (Da)
    66,143
  • Last updated
    2009-11-03 v1
  • MD5 Checksum
    7795169634F69E2EE837A87CF828CA3A
MSQHVKSPEPTESPKPRQKPGAACEECRRRKLRCDRRQPQCRLCEASGVECQVITARPSRGPKPALEGALLQQSTTNFSGPTDDHPLDTPMLDDQIDLSGWQLPVMDDESSLNGVYAASKANSSSGTIMTNAGSGVNSISPPHRSSSIPVELTMPDVGSHIKGMENVEDICEPKISDLIQADLDQLYFDRIHHFMPIQHQSCYFSWRRQPIKTEAQSCLQYAIWTLGASVSALHENIGHSFYQYARRGLEALDSKNMSLASTDLEQVQAWLLLAIHEFMSVDFRRGWISAGRAFRLIQLNWLHGTDGWDLTRAQTDWIETEQKRRTFWMAYCLDRFMSMRTGSPPTFSERVAIRLPCPEANFQNDQPILMGFLSDALAADTSITSTFTECIVVATISGRALSHRNQCLAGDLYFSAVDDFWNRHQWINAILTQRMEAFSAKYPLDMQQQTDPMLLFISLMWRTIILHLYQTMACVIPSHDEKRDLVTEYKKRSSAAAQEIVDLTNKLSHLNSLKVHPLTPIPLSLCVEFLILYHKPGDVFTKQLQDITEAMRNLKRFSNLGQEVLQLFDDQLLTTSPFQSSTVH

Sequence caution

The sequence EAA59550.1 differs from that shown. Reason: Erroneous gene model prediction

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AACD01000135
EMBL· GenBank· DDBJ
EAA59550.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.
BN001302
EMBL· GenBank· DDBJ
CBF73479.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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