C7YS44 · PGH_FUSV7

Function

function

Serine-type endopeptidase that cleaves Gly-Gly bonds in the polyglycine linker of host plant class IV chitinases to disrupt their chitin-binding, and thereby plays a role in lowering the defense responses of the host to the fungus (PubMed:36762862).
Degrades Z.mays Endochitinase A (CHIA) in vitro, although corn is not its host species (PubMed:35240278, PubMed:36762862).

Features

Showing features for active site.

163650100150200250300350400450500550600
TypeIDPosition(s)Description
Active site363

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentextracellular region
Molecular Functionserine-type endopeptidase activity
Biological Processeffector-mediated suppression of host defense response

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Polyglycine hydrolase
  • EC number
  • Alternative names
    • Chitinase modifying protein
      (Fvan-CMP
      )

Gene names

    • ORF names
      NECHADRAFT_40822

Organism names

Accessions

  • Primary accession
    C7YS44

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Phenotypes & Variants

Features

Showing features for mutagenesis.

TypeIDPosition(s)Description
Mutagenesis554Decreases protein level with no apparent gain of beta-lactamase activity; when associated with 583-K--T-584.
Mutagenesis583-584Decreases protein level with no apparent gain of beta-lactamase activity; when associated with G-554.

PTM/Processing

Features

Showing features for signal, chain, glycosylation, disulfide bond.

TypeIDPosition(s)Description
Signal1-22
ChainPRO_500298862323-636Polyglycine hydrolase
Glycosylation30N-linked (GlcNAc...) asparagine
Disulfide bond141↔175
Glycosylation151N-linked (GlcNAc...) asparagine
Glycosylation383N-linked (GlcNAc...) asparagine
Glycosylation481N-linked (GlcNAc...) asparagine

Keywords

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region512-540Disordered

Sequence similarities

Belongs to the peptidase S12 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    636
  • Mass (Da)
    70,412
  • Last updated
    2009-10-13 v1
  • Checksum
    029A04BD0E26D0A1
MHSLSLRRLLTSVLSLCSCSSALPNQRRSNVTSHVETYYSVDGATHAEKSKALKADGYRIVSLSSYGSPDSANYAAIWVQEEGPSFEIIHDADEATYNSWLQTWKSRGYVSTQVSATGPAENAVFAGVMENINVANWFQSCELENPWAFSNTTGNVDVVVKGFRMFGTPEERRYCILGHENVGNEQTTIQYSTPSFTVNFASTFEAETTKRFWRPSRLFLSEDHIITPSFADTSVGKWSHAVDLTKAELKEKIETERAKGLYPIDIQGGGSGSSERFTVVFAERTSPKPRQWNVRGEITGFEDNKAAEEEVDSIMRRFMEKNGVRQAQFAVALEGKTIAERSYTWAEDDRAIVEPDDIFLLASVSKMFLHASIDWLVSHDMLNFSTPVYDLLGYKPADSRANDINVQHLLDHSAGYDRSMSGDPSFMFREIAQSLPTKGAKAATLRDVIEYVVAKPLDFTPGDYSAYSNYCPMLLSYVVTNITGVPYLDFLEKNILDGLNVRLYETAASKHTEDRIVQESKNTGQDPVHPQSAKLVPGPHGGDGAVKEECAGTFAMAASASSLAKFIGSHAVWGTGGRVSSNRDGSLSGARAYVESRGTIDWALTLNTREYISETEFDELRWYSLPDFLSAFPIAG

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
GG698899
EMBL· GenBank· DDBJ
EEU45181.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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