C7YRU9 · C7YRU9_FUSV7

Function

function

As part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentchromatin
Cellular Componentchromosome, telomeric repeat region
Cellular Componentcondensed nuclear chromosome
Cellular Componentcytosol
Cellular ComponentDNA replication factor A complex
Cellular Componentsite of double-strand break
Molecular Functiondouble-stranded DNA binding
Molecular Functionmetal ion binding
Molecular Functionsequence-specific DNA binding
Molecular Functionsingle-stranded DNA binding
Biological ProcessDNA topological change
Biological ProcessDNA unwinding involved in DNA replication
Biological Processdouble-strand break repair via homologous recombination
Biological Processestablishment of protein localization
Biological Processheteroduplex formation
Biological Processmitotic DNA replication
Biological Processnucleotide-excision repair
Biological Processpremeiotic DNA replication
Biological Processprotein ubiquitination
Biological Processreciprocal meiotic recombination
Biological Processsporulation
Biological Processtelomere maintenance via recombination
Biological Processtelomere maintenance via telomerase

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Replication protein A subunit

Gene names

    • ORF names
      NECHADRAFT_69505

Organism names

Accessions

  • Primary accession
    C7YRU9

Proteomes

Organism-specific databases

Interaction

Subunit

Component of the heterotrimeric canonical replication protein A complex (RPA).

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain7-108Replication factor-A protein 1 N-terminal
Region143-172Disordered
Compositional bias147-168Polar residues
Domain188-261OB
Domain297-394Replication protein A OB
Domain453-599Replication factor A C-terminal

Sequence similarities

Belongs to the replication factor A protein 1 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    611
  • Mass (Da)
    68,042
  • Last updated
    2009-10-13 v1
  • Checksum
    D18522C983AC2F2E
MAAASALSRGALDVIFNDPDKAAKLFPVPVLQCLQVKQMAPSAQGGERYRLVMSDGQHYVQTMLATQANHVVRDNKLVRGCFARIKQYTPNNLKGKNILVILDLEVVESLGIQDKIGEPVAVDAKPPGQEGAIAGGDFYGVKKEEQKPQPQQFQQQQQQQQSMPSRPAMHGGSNIYPIEGLSPFAHKWTIKARVTSKSDIKTWHKATGEGKLFSVNLLDESGEIKATGFNEQCDAFYDRLQEGSVYYISTPCRVSLAKKQFSNLPNDYELAFERDTVIEKAEDQTNVPQVRFNFCTIQELQSVEKDNTVDVIGVLKEVGEIGEIVSKKDGRPFQKRELTLVDDTGYSVRVTVWGKTANSFDAPAESVVAFKGTKVSDFGGKSLSLLSSGTMSVDPDIADAHRLKGWYDSAGRTDTFATHQGMASMGNATGRKDEIKTISQVKDENLGMDDQAYYTIKATIVFMKQDTFCYPACASQGCNKKVTEMGDGTWHCEKCNVSHEKPEYRYILSLNVADHTSHQWLSCFDDSGQKILGRTANEMMELKESDDPTKFTAAFEEANCKKLTFRCRAKMDNFGEAQRIRYQVMSAMPLDFTSEGNKLKEMIKEYENMGM

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias147-168Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
GG698899
EMBL· GenBank· DDBJ
EEU45135.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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